Suprainguinal Fascia Iliaca Block With vs Without Dexmedetomidine

Part of paid clinical trials in Providence, Rhode Island.

Sponsor
Rhode Island Hospital
Study ID
NCT07316166
Phase
PHASE4
Status
Recruiting
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Conditions

  • Postoperative Pain Management

Eligibility Criteria

Sex
ALL
Age
18 Years - 80 Years
Healthy Volunteers
Not accepted

Interventions

  • Dexmedetomidine — DRUG
    Participants in the experimental arm receive a preoperative suprainguinal fascia iliaca block consisting of 30 mL of 0.25% ropivacaine combined with perineural dexmedetomidine at a dose of 1 mcg/kg.
  • Ropivacaine — DRUG
    In the experimental arm, ropivacaine (30 mL of 0.25%) is administered with dexmedetomidine. In the active comparator arm, ropivacaine (30 mL of 0.25%) is administered alone without any dexmedetomidine medication.

Study Details

The investigators are evaluating postoperative outcomes in patients undergoing hip replacement surgery performed with either spinal or general anesthesia, who also receive a suprainguinal fascia iliaca block using either perineural ropivacaine alone or ropivacaine combined with dexmedetomidine.

Key Dates

Start date
Jan 20, 2026
Status verified
Mar 2026
Primary completion
Jun 30, 2027
Completion
Jun 30, 2027

Study Design

Enrollment
120 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE

Arms

  • Active Comparator: Ropivacaine
    30 ml of 0.25% ropivacaine; No dexmedetomidine
  • Experimental: Ropivacaine plus Dexmedetomidine
    30 ml of 0.25% ropivacaine; 1 mcg/kg of dexmedetomidine

Primary Outcome Measure

Time of administration of first analgesic after the surgery [ Time Frame: Time to first analgesic request, defined as the interval (in minutes) from block administration to the first request for rescue analgesia, assessed for up to 24 hours. ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
The Miriam HospitalProvidenceRhode Island02906
Renee Dupre
[email protected]
401-793-4575
Mark Kendall, M.D.
[email protected]
401-444-4722

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By research site
The Miriam Hospital· Providence, RI

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