Researching Economical Adjuvants to Cancer Therapy

Part of paid clinical trials in Tallahassee, Florida.

Sponsor
Florida State University
Study ID
NCT07305259
Phase
EARLY_PHASE1
Status
Recruiting
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Conditions

  • Healthy Participants

Eligibility Criteria

Sex
ALL
Age
18 Years - 45 Years
Healthy Volunteers
Accepted

Interventions

  • Beta-glucan — DIETARY_SUPPLEMENT
    375mg of beta-glucan in the form of a ground mushroom powder. The supplement is provided in capsule form.
  • Placebo — DIETARY_SUPPLEMENT
    375mg of microcrystalline cellulose in capsule form.

Study Details

The goal of this clinical trial is to learn if beta-glucan (a dietary fiber) improves the function of the immune system in adults. It will also tell the investigators if combining beta-glucan with single bouts of exercise provides additional benefit. The main questions it aims to answer are: 1. Does beta-glucan change the ability of immune cells to recognize cancer cells? 2. Does exercise change the type of immune cells in the blood? Researchers will compare beta-glucan to a placebo (a look-alike substance with no effect) to see if beta-glucan could improve immune function against cancer. Participants will: 1. Take beta-glucan or a placebo daily for 4 weeks. 2. Visit the laboratory for three exercise tests. 3. Provide blood samples so researchers can study immune system cells.

Key Dates

Start date
Nov 12, 2025
Status verified
Dec 2025
Primary completion
Sep 30, 2029
Completion
Sep 30, 2029

Study Design

Enrollment
60 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: Beta-glucan
    375mg of beta-glucan is provided daily for 4 weeks.
  • Placebo Comparator: Placebo
    375mg of cellulose daily for 4 weeks.

Primary Outcome Measure

Cellular Cytotoxicity Assessed With Flow Cytometry [ Time Frame: At baseline, the end of treatment at four weeks, and at eight weeks after a washout phase. ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Institute of Sports Sciences and MedicineTallahasseeFlorida32306
Kyle A Smith, PhD, RD
[email protected]
8506451016
Kyle A Smith, PhD, RD (PRINCIPAL_INVESTIGATOR)

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Institute of Sports Sciences and Medicine· Tallahassee, FL

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