Transforming Research and Clinical Knowledge in Geriatric Traumatic Brain Injury (TRACK-GERI)

Part of paid clinical trials in San Francisco, California.

Sponsor
University of California, San Francisco
Study ID
NCT07296783
Status
Enrolling By Invitation

Conditions

  • Traumatic Brain Injury

Eligibility Criteria

Sex
ALL
Age
65 Years - N/A
Healthy Volunteers
Accepted

Study Details

The purpose of this study is to improve the diagnosis and prediction of recovery after traumatic brain injury (TBI) in adults age 65 years and older. The study will follow older adults who present to the emergency department after TBI, as well as matched control participants, and will measure clinical features, brain imaging, and blood-based biomarkers over 12 months to understand how recovery changes over time. Researchers will examine how pre-injury health, brain structure, and biological markers are related to disability and cognitive outcomes after TBI. Information from this study will be used to develop age-appropriate tools to better diagnose TBI and estimate long-term outcomes in older adults.

Key Dates

Start date
Sep 2, 2019
Status verified
Dec 2025
Primary completion
Jan 31, 2027
Completion
Jan 31, 2027

Study Design

Enrollment
1,500 participants (estimated)

Arms

  • Arm: TRACK-GERI TBI Patients
    TBI patients
  • Arm: TRACK-GERI Study Partners of TBI Patients
    Study partners of TBI patients
  • Arm: TRACK-GERI Controls
    Controls
  • Arm: TRQACK-GERI Study Partners of Control Patients
    Study partners of control patients
  • Arm: TRACK-VA TBI Patients
    VA TBI patients
  • Arm: TRACK-VA Study Partners of TBI Patients
    Study partners of VA TBI patients
  • Arm: TRACK-VA Controls
    VA controls
  • Arm: TRACK-VA Study Partners of Control Patients
    Study partners of VA control patients

Primary Outcome Measure

Functional Outcome at 6 Months Post-Injury as Assessed by the Glasgow Outcome Scale-Extended (GOSE) [ Time Frame: 6 months post-injury ]

Locations (3)

FacilityCityStateZIPSite coordinators
San Francisco Veterans Affairs Medical CenterSan FranciscoCalifornia94121-
University of California, San FranciscoSan FranciscoCalifornia94110-
University of PittsburghPittsburghPennsylvania15213-

Find similar trials in San Francisco, CA

By research site
San Francisco Veterans Affairs Medical Center· San Francisco, CAUniversity of California, San Francisco· San Francisco, CAUniversity of Pittsburgh· Pittsburgh, PA

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