Infusion of Lidocaine and Steroids in Middle Meningeal Artery for Pain in Subarachnoid Hemorrhage

Part of paid clinical trials in Galveston, Texas.

Sponsor
The University of Texas Medical Branch, Galveston
Study ID
NCT07294118
Phase
PHASE2
Status
Recruiting
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Conditions

  • Headache
  • Opiate Dependence
  • Opioid Use
  • Subarachnoid Hemorrhage, Aneurysmal

Eligibility Criteria

Sex
ALL
Age
18 Years - 100 Years
Healthy Volunteers
Not accepted

Interventions

  • Lidocaine — DRUG
    The participants will receive 50 mg of lidocaine.
  • Lidocaine and Dexamethasone — DRUG
    The participants will receive 50 mg of lidocaine and 10 mg of dexamethasone one after the other.

Study Details

The goal of this clinical trial is to learn if an infusion of lidocaine, with or without steroids, into the middle meningeal artery (MMA) helps relieve severe headaches in patients with spontaneous subarachnoid hemorrhage (SAH). It will also study the safety of this treatment.

Key Dates

Start date
Jan 2, 2026
Status verified
Jan 2026
Primary completion
Jun 30, 2027
Completion
Aug 31, 2027

Study Design

Enrollment
15 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Lidocaine (50 mg bilaterally)
    The participants will receive 50 mg of lidocaine.
  • Experimental: Lidocaine (50 mg) + Dexamethasone (10 mg bilaterally)
    The participant will receive Lidocaine (50 mg) + Dexamethasone (10 mg bilaterally)
  • No Intervention: No injection (Control group)
    The participant will not receive an injection.

Primary Outcome Measure

Visual Analog Scale (VAS) Score [ Time Frame: Baseline ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Texas Medical Branch, GalvestonGalvestonTexas77555-0158
Matias Costa
[email protected]
409-772-1011
Peter Kan, MD (PRINCIPAL_INVESTIGATOR)

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