Understanding Practices of Lactation and Infant Feeding Together With Women With HIV in the United States
Part of paid clinical trials in Los Angeles, California.
- Sponsor
- International Maternal Pediatric Adolescent AIDS Clinical Trials Group
- Study ID
- NCT07293559
- Status
- Recruiting
Conditions
- Breastfeeding
- HIV-1-infection
- Pregnancy Related
Eligibility Criteria
- Sex
- ALL
- Age
- N/A - N/A
- Healthy Volunteers
- Accepted
Interventions
- No intervention provided in this study — OTHERNone; No intervention provided in this study
Study Details
IMPAACT 2046/UPLIFT (Understanding Practices of Lactation and Infant Feeding decisions Together with women with HIV) is a multi-site, mixed-methods, observational cohort study. The purpose of the study is to explore infant feeding preferences, practices, and outcomes among mothers with HIV and their families in the United States. It will employ both qualitative and quantitative research methods to address existing knowledge gaps and to understand the clinical, behavioral, and social factors influencing infant feeding decisions. As part of the study's mixed method approach, a longitudinal cohort study of mothers and their infants will be established. The study also aims to pilot a national registry of breastfeeding women living with HIV in the United States.
Key Dates
- Start date
- Feb 24, 2026
- Status verified
- Mar 2026
- Primary completion
- Apr 24, 2031
- Completion
- Apr 24, 2031
Study Design
- Enrollment
- 1,150 participants (estimated)
Arms
- Arm: Core Activity 1This core activity aims to explore current site-level infant feeding practices and infant feeding decision-making and preferences at selected sites in the US.
- Arm: Core Activity 2This core activity aims to examine infant feeding practices and outcomes among women with HIV at selected sites in the US and to describe the financial implications of different infant feeding choices.
- Arm: Core Activity 3This core activity aims to pilot and assess the feasibility and acceptability of a national registry of breastfeeding women with HIV in the US.
Primary Outcome Measure
CA 1: Factors influencing infant feeding decision [ Time Frame: Within 28 days and 2 years of Enrollment ]
Central Contacts
- Lisa Levy202-884-8480
Locations (11)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| David Geffen School of Medicine at UCLA (CRS 5112) | Los Angeles | California | 90095 | |
| University of Southern California (CRS 5048) | Los Angeles | California | 90089 | |
| University California, San Diego (CRS 4601) | San Diego | California | 92103 | Stephen Spector, MD (PRINCIPAL_INVESTIGATOR) |
| University of Colorado, Denver (CRS 5052) | Aurora | Colorado | 80045 | |
| University of Florida (5051) | Jacksonville | Florida | 32209 | Mobeen Rathore, MD (PRINCIPAL_INVESTIGATOR) |
| Univ of Miami Pediatric/Perinatal HIV/AIDS (5127) | Miami | Florida | 33136 | |
| 5030, Emory University School of Medicine Clinical Research Site | Atlanta | Georgia | 30322 | Andres Camacho-Gonzalez LaTeshia Thomas-Seaton |
| Lurie Children's Hospital of Chicago (CRS 4001) | Chicago | Illinois | 60614 | |
| Johns Hopkins University (CRS 5092) | Baltimore | Maryland | 21287 | |
| Jacobi Med. Ctr. Bronx NICHD CRS (5013) | The Bronx | New York | 10461 | |
| St. Jude Childrens Research Hosp, Memphis (6501) | Memphis | Tennessee | 38105 |
Find similar trials in Los Angeles, CA
Related Studies
- POWERMOM, A Healthy Pregnancy Research CommunityRecruiting · Scripps Translational Science Institute · La Jolla, California
- Pharmacokinetics Distribution of Raltegravir by PET/MREARLY_PHASE1 · Recruiting · University of California, San Francisco · San Francisco, California
- PET Imaging of Radiolabeled Anti-HIV-1 Envelope Monoclonal Antibody (VRC01)PHASE1 · Recruiting · University of California, San Francisco · San Francisco, California
- Safety Study for Prospective Assessment of Pregnancy Outcomes in Patients Treated With TildrakizumabRecruiting · Sun Pharmaceutical Industries Limited · San Diego, California