A Study of Multiparametric Ultrasound Imaging Methods

Conditions

• Pancreatic Cancer
• Thyroid Nodule

Eligibility Criteria

Sex

ALL

Age

18 Years - N/A

Healthy Volunteers

Accepted

Interventions

• Multiparametric ultrasound (mpUS) imaging — DIAGNOSTIC_TEST
  Patients will undergo the added research sequences at any point during their standard of care ultrasound scans, adding up to approximately 15 minutes of added scan time. The only non-routine measurements will be the research ultrasound data.

Study Details

The researchers are doing this study to see how well a type of ultrasound imaging called multiparametric ultrasound (mpUS), can be used to examine, evaluate, and provide information about different cancerous and non-cancerous tissue. The researchers will compare the results of mpUS imaging to standard ultrasound imaging and other standard tests. mpUS imaging is a type of ultrasound imaging that combines different ultrasound methods and analysis to create a more detailed and accurate assessment of tissue. Standard ultrasound provides a basic image of tissue structure, but mpUS imaging can also show blood vessels, blood flow, and detailed tissue structure (microstructure). The researchers think that mpUS may be a better way for evaluating cancer because it combines different ultrasound methods to assess tissue.

Key Dates

Start date

Nov 24, 2025

Status verified

Dec 2025

Primary completion

Nov 30, 2027

Completion

Nov 30, 2027

Study Design

Enrollment

85 participants (estimated)

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

DIAGNOSTIC

Arms

• Experimental: Multiparametric endoscopic (mpEUS) imaging of patients at high-risk for pancreatic cancer
  Subjects will undergo add-on mpEUS imaging during their standard of care EUS imaging and will add up to approximately 15 minutes of added scan time.
• Experimental: Multiparametric endoscopic (mpEUS) imaging of patients with pancreatic ductal adenocarcinoma
  Subjects will undergo add-on mpEUS imaging during their standard EUS procedure and will add up to approximately 15 minutes of added scan time.
• Experimental: Thyroid nodule assessment with multiparametric ultrasound (mpUS) imaging
  Subjects will undergo add-on mpUS imaging at the beginning of their standard of care ultrasound procedure and will add up to approximately 5 minutes of added scan time.

Primary Outcome Measure

investigate the feasibility of mpEUS imaging [ Time Frame: 1 day ]

Central Contacts

• Mark T Burgess, PhD
  646-608-8284
  [email protected]
• Wyanne Law, MD
  [email protected]

Locations (7)

Find similar trials in Basking Ridge, NJ

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