Towards Restoring Complex Movement After Paralysis: Algorithm Development With Healthy Participants

Part of paid clinical trials in Los Angeles, California.

Sponsor
University of California, Los Angeles
Study ID
NCT07236892
Status
Recruiting
Apply to this trial

Conditions

  • Movement Disorders
  • Neurorehabilitation
  • Non-invasive Activity Recording

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • Participants will perform experimental tasks while undergoing non-invasive activity recordings, which may include EEG, EMG, IMUs, fNIRS, eye gaze, or pupillometry. — BEHAVIORAL
    Participants may be prompted to imagine, attempt, or perform actions while a task is being performed on a computer, robotic arm, wheelchair, or exoskeleton. Participants may also autonomously perform actions to control each end effector. Participants may be asked to control a cursor to acquire a target or multiple targets. Participants may be asked to pick and place various objects, interact with articulated objects, or perform other motor tasks using a robotic manipulator. Participants may be asked to navigate a wheelchair.

Study Details

Participants will perform experiments with non-invasive activity recordings. The study will record from multiple non-invasive signal sources that reflect motor intent that may include: electroencephalography (EEG), electromyography (EMG), functional near infrared spectroscopy (fNIRS), inertial measurement units (IMUs), eye movements, pupil size, and speech. Participants will wear all or a subset of these sensors and be asked to perform, imagine, or attempt movements or speech. The recorded sensor signals will be decoded to help guide an end effector, which may be a computer, robotic arm, wheelchair, or other assistive device. These experiments present minimal risk and participants may withdraw participation at any time for any reason. Participants may return for additional experiments if desired and to perform additional comparisons. If a participant withdraws during a comparison, another participant will be recruited to complete collection of data for that comparison.

Key Dates

Start date
Nov 26, 2025
Status verified
Dec 2025
Primary completion
Dec 1, 2029
Completion
Dec 1, 2029

Study Design

Enrollment
50 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: Healthy Participants
    Participants will perform a subset of tasks while non-invasive activity is recorded which may include EEG, EMG, IMUs, fNIRS, eye gaze, or pupillometry.

Primary Outcome Measure

Normalized Performance [ Time Frame: Usually one visit (Day 1), with possible additional study visits usually within a month. ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
UCLA Neural Engineering and Computation LabLos AngelesCalifornia90095
Restoring Movement Study Coordinator
[email protected]
310-983-3068

Find similar trials in Los Angeles, CA

By research site
UCLA Neural Engineering and Computation Lab· Los Angeles, CA

Related Studies