A Study of Retatrutide (LY3437943) in Participants With Obesity or Overweight

Part of paid clinical trials in Riverside, California.

Sponsor
Eli Lilly and Company
Study ID
NCT07232719
Phase
PHASE3
Status
Active Not Recruiting

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Retatrutide — DRUG
    Administered SC
  • Placebo — DRUG
    Administered SC

Study Details

The purpose of this study is to evaluate the efficacy and safety of retatrutide compared with placebo for body weight reduction. Participation in the study will last about 65 weeks and may include about 18 visits.

Key Dates

Start date
Nov 17, 2025
Status verified
Apr 2026
Primary completion
Jul 31, 2027
Completion
Jul 31, 2027

Study Design

Enrollment
250 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Retatrutide Dose 1
    Participants will receive retatrutide subcutaneously (SC)
  • Experimental: Retatrutide Dose 2
    Participants will receive retatrutide SC
  • Placebo Comparator: Placebo
    Participants will receive placebo SC

Primary Outcome Measure

Percent Change from Baseline in Body Weight [ Time Frame: Baseline, Week 56 ]

Locations (19)

FacilityCityStateZIPSite coordinators
Artemis Institute for Clinical ResearchRiversideCalifornia92503-
JEM Research InstituteAtlantisFlorida33462-
Headlands Research OrlandoOrlandoFlorida32806-
Care Access - TamaracTamaracFlorida33321-
Care Access - Arlington HeightsArlington HeightsIllinois60005-
L-MARC Research CenterLouisvilleKentucky40213-
IMA Clinical Research Monroe - ArmandMonroeLouisiana71201-
Pharmasite Research, Inc.BaltimoreMaryland21208-
Clinical Research ProfessionalsChesterfieldMissouri63005-
Clinvest Headlands LlcSpringfieldMissouri65807-
IMA Clinical Research WarrenWarren TownshipNew Jersey07059-
IMA Clinical Research ManhattanNew YorkNew York10036-
Trial Management Associates - Wilmington - Floral ParkwayWilmingtonNorth Carolina28403-
Cedar Health ResearchDallasTexas75251-
Headlands Research-El PasoEl PasoTexas79902-
Cedar Health Research - EulessEulessTexas76040-
Cedar Health Research - Fort WorthFort WorthTexas76132-
Care Access - HoustonHoustonTexas77054-
IMA Clinical Research San AntonioSan AntonioTexas78229-

Find similar trials in Riverside, CA

By condition
Obesity / overweight
By specialty
EndocrinologyMetabolic healthWeight loss
By research site
Artemis Institute for Clinical Research· Riverside, CAJEM Research Institute· Atlantis, FLHeadlands Research Orlando· Orlando, FLCare Access - Tamarac· Tamarac, FLCare Access - Arlington Heights· Arlington Heights, ILL-MARC Research Center· Louisville, KY

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