Intravitreal (IVT) Pozelimab for Geographic Atrophy (GA) in Adult Participants

Part of paid clinical trials in Lakewood, Colorado.

Sponsor
Regeneron Pharmaceuticals
Study ID
NCT07230834
Phase
PHASE1
Status
Recruiting
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Conditions

  • Geographic Atrophy (GA)

Eligibility Criteria

Sex
ALL
Age
50 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Pozelimab — DRUG
    Administered per the protocol

Study Details

This study is researching an experimental drug called pozelimab (called "study drug"). The study is focused on people with a condition where certain parts of the eye's retina stop working over time, which can make it harder to see. This is called geographic atrophy (GA). The aim of the study is to see how safe and tolerable the study drug is when used as an injection in the eye. The study is looking at several other research questions, including: * What side effects may happen from taking the study drug * How much study drug is in the blood and the fluid in the eye at different times * Whether the body makes antibodies against the study drug (which could make the drug less effective or could lead to side effects)

Key Dates

Start date
Jan 19, 2026
Status verified
Mar 2026
Primary completion
Jul 3, 2028
Completion
Jul 3, 2028

Study Design

Enrollment
54 participants (estimated)
Allocation
RANDOMIZED
Intervention model
SEQUENTIAL
Primary purpose
TREATMENT

Arms

  • Experimental: Part A
  • Experimental: Part B

Primary Outcome Measure

Occurrence of ocular Treatment-Emergent Adverse Event (TEAEs) in the study eye [ Time Frame: Through week 8 ]

Central Contacts

Locations (5)

FacilityCityStateZIPSite coordinators
Colorado Retina AssociatesLakewoodColorado80228-
Ophthalmic Consultants of BostonEast WeymouthMassachusetts02189-
Austin Retina AssociatesAustinTexas78705-
Retina Foundation of the SouthwestDallasTexas75231-
Retina Consultants TexasThe WoodlandsTexas77384-

Find similar trials in Lakewood, CO

By research site
Colorado Retina Associates· Lakewood, COOphthalmic Consultants of Boston· East Weymouth, MAAustin Retina Associates· Austin, TXRetina Foundation of the Southwest· Dallas, TXRetina Consultants Texas· The Woodlands, TX

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