Giving Asthmatics Intramuscular Steroids for Preventing Return to the Emergency Department

Part of paid clinical trials in The Bronx, New York.

Sponsor
Montefiore Medical Center
Study ID
NCT07228052
Phase
PHASE4
Status
Not Yet Recruiting

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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Dexamethasone 16mg IM — DRUG
    Dexamethasone 16mg Intramuscular Administration Once
  • Prednisone 60mg PO — DRUG
    Prednisone 60mg PO for 5 Days

Study Details

This study aims to compare the efficacy of a one-time IM dose of dexamethasone versus a 5-day course of prednisone in adult ED patients presenting with asthma exacerbations. This is a randomized, controlled, double-blind, non-inferiority trial conducted at two urban EDs within the Montefiore Health System.

Key Dates

Start date
Apr 30, 2026
Status verified
Mar 2026
Primary completion
Sep 30, 2026
Completion
Sep 30, 2026

Study Design

Enrollment
182 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Active Comparator: Single Intramuscular Steroid Injection
    Dexamethasone 16mg Intramuscular Single Dose
  • Active Comparator: Oral Steroid Short Course
    Prednisone 60mg PO for 5 Days

Primary Outcome Measure

Asthma Control Test Score [ Time Frame: Within 4 Weeks post-discharge, up to 28-30 days ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Montefiore Medical CenterThe BronxNew York10467
Mustfa Manzur, MD MPH MS
[email protected]
718-920-6626

Find similar trials in The Bronx, NY

By condition
Asthma
By specialty
PulmonologyLung disease
By research site
Montefiore Medical Center· The Bronx, NY

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