Human Thalamus in Propagation of Temporal Lobe Seizures and Memory Formation

Part of paid clinical trials in Stanford, California.

Sponsor
Stanford University
Study ID
NCT07226908
Status
Enrolling By Invitation

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 65 Years
Healthy Volunteers
Not accepted

Interventions

  • Cognitive experiment — OTHER
    Record brain activity during memory encoding
  • Electrical stimulation of the brain — OTHER
    Measure accuracy and reaction time during cognitive tasks

Study Details

The goal of the study is to examine how two key subregions of the human thalamus (ANT and PLV) are connected with other brain structures (Aim 1), how seizures involve the two thalamic subregions differently and how the map of cortico-thalamic ictal propagation matches the intrinsic connectivity maps identified in the same individuals (Aim 2), and the effect of ANT and PLV stimulations on memory formation (Aim 3).

Key Dates

Start date
Sep 1, 2024
Status verified
Aug 2025
Primary completion
Aug 31, 2029
Completion
Aug 31, 2029

Study Design

Enrollment
100 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE

Arms

  • Other: Epilepsy Patients with Thalamic Electrode Implants
    Patients will undergo cognitive testing and electrical stimulation experiments.

Primary Outcome Measure

Cerebro-cerebral evoked potentials [ Time Frame: During experiment up to 2 weeks ]

Locations (1)

FacilityCityStateZIPSite coordinators
Stanford HospitalStanfordCalifornia94304-

Find similar trials in Stanford, CA

By condition
Epilepsy
By specialty
NeurologyBrain disorders
By research site
Stanford Hospital· Stanford, CA

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