NBTXR3 With Radiation Therapy Alone for Locally-advanced Non-small Cell Lung Cancer

Part of paid clinical trials in Houston, Texas.

Sponsor
M.D. Anderson Cancer Center
Study ID
NCT07224152
Phase
PHASE1/PHASE2
Status
Recruiting
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Conditions

  • Locally-Advanced Non-Small Cell Lung Cancer

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • NBTXR3 — DRUG
    Given by injection

Study Details

This is a single institution, single arm phase I/II study of NBTXR3 with radiation therapy for stage I-III advanced non-small cell lung cancer patients who are not candidates for chemotherapy or surgical resection.

Key Dates

Start date
Mar 27, 2026
Status verified
Mar 2026
Primary completion
Aug 30, 2028
Completion
Aug 30, 2030

Study Design

Enrollment
40 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Phase I/II: Treatment with NBTXR3 + Radiation Therapy

Primary Outcome Measure

Safety and Adverse Events (AEs) [ Time Frame: Through study completion; an average of 1 year ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
The University of Texas M. D. Anderson Cancer CenterHoustonTexas77030
Aileen Chen, MD
[email protected]
713-745-6293
Aileen Chen, MD (PRINCIPAL_INVESTIGATOR)

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The University of Texas M. D. Anderson Cancer Center· Houston, TX