A Long Term Extension Study to Evaluate the Safety and Efficacy of Afimkibart (RO7790121) in Participants With Atopic Dermatitis

Part of paid clinical trials in Alpharetta, Georgia.

Sponsor
Hoffmann-La Roche
Study ID
NCT07223697
Phase
PHASE2
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Afimkibart — DRUG
    Afimkibart SC injection will be administered as per the schedule defined in the protocol.

Study Details

This study will assess long-term safety and efficacy of Afimkibart (also known as RO7790121) in participants with Atopic Dermatitis (AD) who participated in previous afimkibart clinical trials.

Key Dates

Start date
Jan 8, 2026
Status verified
Jun 2026
Primary completion
Mar 1, 2033
Completion
Mar 1, 2033

Study Design

Enrollment
120 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Afimkibart Group I
    Participants will receive Afimkibart as subcutaneous (SC) injection.
  • Experimental: Afimkibart Group II
    Participants will receive Afimkibart as SC injection.

Primary Outcome Measure

Percentage of Participants with Adverse Events [ Time Frame: From Baseline up to 6 years ]

Central Contacts

  • Reference Study ID Number: CS45943 https://forpatients.roche.com/
    888-662-6728 (U.S. and Canada)
    [email protected]
  • Fastest response: use the inquiry form. No email attachments. https://www.gene.com/contact-us/submit-medical-inquiry

Locations (3)

FacilityCityStateZIPSite coordinators
Hamilton Research, LLCAlpharettaGeorgia30022-
Revival Research Institute, LLCTroyMichigan48084-
Best Skin Research LLCCamp HillPennsylvania17011-

Find similar trials in Alpharetta, GA

By condition
Atopic dermatitis / eczema
By specialty
DermatologyRheumatologyAutoimmune disease
By research site
Hamilton Research, LLC· Alpharetta, GARevival Research Institute, LLC· Troy, MIBest Skin Research LLC· Camp Hill, PA

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