Weight Loss in People Living With Overweight or Obesity Following Treatment With Cagrilintide

Part of paid clinical trials in Walnut Creek, California.

Sponsor
Novo Nordisk A/S
Study ID
NCT07220642
Phase
PHASE3
Status
Active Not Recruiting

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Cagrilintide — DRUG
    Cagrilintide will be administered subcutaneously with a pen-injector as an adjunt to lifestyle intervention counselling.
  • Placebo — DRUG
    Placebo matched to cagrilintide will be administered subcutaneously with a pen-injector as an adjunt to lifestyle intervention counselling.

Study Details

This study will look at how much cagrilintide helps people with overweight or obesity lower their body weight. Cagrilintide is a new investigational medicine. Doctors may not yet prescribe cagrilintide. Participants will either get cagrilintide or placebo. Which treatment participants get is decided by chance. Participants are two times more likely to get cagrilintide than placebo. Like all medicines, the study medicine may have side effects. Possible side effects will be followed carefully during the study. For each participant, the study will last for about 1 year and 6 months.

Key Dates

Start date
Nov 5, 2025
Status verified
Apr 2026
Primary completion
May 11, 2027
Completion
Jun 29, 2027

Study Design

Enrollment
300 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Cagrilintide
    Participants will receive cagrilintide subcutaneously once weekly for 64 weeks.
  • Placebo Comparator: Placebo
    Participants will receive placebo matched to cagrilintide subcutaneously once weekly for 64 weeks.

Primary Outcome Measure

Relative change in body weight [ Time Frame: From baseline (week 0) to end of treatment (week 64) ]

Locations (9)

FacilityCityStateZIPSite coordinators
Diablo Clinical Research, Inc.Walnut CreekCalifornia94598-
Univ of Colorado at DenverAuroraColorado80045-
Florida Inst For Clin Res LLCOrlandoFlorida32825-
Oviedo Medical Research, LLCOviedoFlorida32765-
Walgreens - Store 11760Oak ParkIllinois60302-
Midwest Inst For Clin ResIndianapolisIndiana46260-
StudyMetrix Research LLCCity of Saint PetersMissouri63303-
PharmQuest Life Sciences LLCGreensboroNorth Carolina27408-
Selma Medical AssociatesWinchesterVirginia22601-3834-

Find similar trials in Walnut Creek, CA

By condition
Obesity / overweight
By specialty
EndocrinologyMetabolic healthWeight loss
By research site
Diablo Clinical Research, Inc.· Walnut Creek, CAUniv of Colorado at Denver· Aurora, COFlorida Inst For Clin Res LLC· Orlando, FLOviedo Medical Research, LLC· Oviedo, FLWalgreens - Store 11760· Oak Park, ILMidwest Inst For Clin Res· Indianapolis, IN

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