Effects of a 5-Week Probiotic Supplementation Intervention on Markers of Delayed Onset Muscle Soreness

Part of paid clinical trials in Minneapolis, Minnesota.

Sponsor
University of Minnesota
Study ID
NCT07219498
Status
Recruiting
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Conditions

  • Delayed Onset Muscle Soreness (DOMS)
  • Exercise Induced Muscle Damage

Eligibility Criteria

Sex
ALL
Age
18 Years - 30 Years
Healthy Volunteers
Accepted

Interventions

  • Lactobacillus casei — DIETARY_SUPPLEMENT
    Probiohealth is the manufacturer of this strain and they use a stringent quality control program that utilizes a multi point product variability check system.
  • Placebo Capsule(s) — OTHER
    The brand name of placebo capsules that will be used in this study is Magic Bullet Placebo Capsules. This placebo is manufactured by Progressive Placebo as stated on the product label.

Study Details

The purpose of this study is to evaluate how probiotic supplementation (PS) influences post-exercise recovery in healthy, physically active young adults. Researchers aim to determine if the Lactobacillus casei probiotic strain reduces symptoms of delayed onset muscle soreness (DOMS) based on perceived muscle soreness, pressure pain threshold, and power output following exercise induced muscle damage (EIMD).

Key Dates

Start date
Feb 5, 2026
Status verified
Apr 2026
Primary completion
Dec 31, 2026
Completion
Dec 31, 2026

Study Design

Enrollment
24 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION

Arms

  • Active Comparator: Probiotic Group
  • Placebo Comparator: Placebo Group

Primary Outcome Measure

Change in perceived muscle soreness [ Time Frame: From baseline to post 5-week intervention ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of MinnesotaMinneapolisMinnesota55455
Jakob Fischer
[email protected]
507-236-8051

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By research site
University of Minnesota· Minneapolis, MN

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