Kava Aging and Mobility Study

Part of paid clinical trials in Gainesville, Florida.

Sponsor
University of Florida
Study ID
NCT07219186
Phase
EARLY_PHASE1
Status
Not Yet Recruiting

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Conditions

  • Kava
  • Mobility Impairment
  • Old Adults
  • Physical Activity and Stress
  • Physical Impairment
  • Sedentary Lifestyle in Patients Over 70
  • Sleep Quality

Eligibility Criteria

Sex
ALL
Age
70 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • AB-free kava — DRUG
    AB-free kava (75mg kavalactones per capsule, for a total of 225 mg/day)
  • Placebo — OTHER
    Participants will consume microcrystalline cellulose in capsules identical to AB-free kava, which will be provided by Thorne Research. There are no active ingredients in the placebo capsules.

Study Details

The goal of this clinical trial is to learn if AB-free kava works to improve mobility and physical function in older adults with sleep difficulties. It will also learn about the safety of AB-free kava. The main questions it aims to answer are: * Does AB-free kava improve physical function and/or mobility? * Does AB-free kava effect sleep, stress, or cellular signaling? Researchers will compare AB-free kava to a placebo (a look-alike substance that contains no drug) to see if AB-free kava works to improve mobility and physical functioning.

Key Dates

Start date
Apr 30, 2026
Status verified
Aug 2025
Primary completion
Mar 31, 2027
Completion
May 31, 2027

Study Design

Enrollment
40 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: AB-free Kava
  • Placebo Comparator: Placebo

Primary Outcome Measure

400-meter walk test [ Time Frame: From baseline to 4 weeks, and again to the end of treatment at 8 weeks. ]

Central Contacts

Locations (2)

FacilityCityStateZIPSite coordinators
Institute on Aging University of FloridaGainesvilleFlorida32610
Stephen D. Anton, Ph.D.
Institute on Aging Unversity of FloridaGainesvilleFlorida32610
Christian W. McLaren, M.S.
[email protected]
863-263-7867
Nevena Stanojevic, B.S.
[email protected]
(352) 294-5824
Stephen D. Anton, Ph.D. (PRINCIPAL_INVESTIGATOR)

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Institute on Aging University of Florida· Gainesville, FLInstitute on Aging Unversity of Florida· Gainesville, FL

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