Phase I Trial of pH Resections of GBM at VA

Part of paid clinical trials in West Los Angeles, California.

Sponsor
VA Office of Research and Development
Study ID
NCT07218367
Phase
PHASE1
Status
Not Yet Recruiting

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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • pH MRI based resection of GBM — PROCEDURE
    This will require a chemical exchange saturation transfer MRI followed by surgical resection based on this MRI.

Study Details

Glioblastoma is an infiltrating tumor that is difficult to visualize in surgery and on standard images. A special pH (acid-base) related magnetic resonance imaging (MRI) has been developed to better see infiltrating tumor. In this safety study, the investigators will carry out increased levels of pH based resections of infiltrating tumor to assess the tolerability in VA populations.

Key Dates

Start date
Jul 1, 2026
Status verified
Feb 2026
Primary completion
Jul 1, 2031
Completion
Jul 1, 2031

Study Design

Enrollment
12 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: pH Resections
    This is a single arm study so all patients will receive the intervention

Primary Outcome Measure

Resection related adverse events [ Time Frame: 1 month ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
VA Greater Los Angeles Healthcare System, West Los Angeles, CAWest Los AngelesCalifornia90073-1003
Kunal S Patel
[email protected]
310-478-3711
Kunal S Patel (PRINCIPAL_INVESTIGATOR)

Find similar trials in West Los Angeles, CA

By condition
Brain cancer
By specialty
OncologyNeuro-oncology
By research site
VA Greater Los Angeles Healthcare System, West Los Angeles, CA· West Los Angeles, CA

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