Orthodontic Pain Alleviation With Chewing Gum

Conditions

• Orthodontic Appliances

Eligibility Criteria

Sex

ALL

Age

N/A - 18 Years

Healthy Volunteers

Not accepted

Interventions

• Xylitol Gum — DRUG
  1 gram of xylitol per piece of gum with one serving being 2 pieces of gum

Study Details

The aim of this study is to determine whether chewing gum can alleviate orthodontic treatment discomfort and improve orthodontic treatment experience. The long-term goal is to enable clinicians to decide whether prescription of chewing gum at the placement of orthodontic appliances can improve patient experience with orthodontic treatment. In specific, a total of 60 patients under the age of 18 will be recruited for the study. Consent will be signed by both the child patient and the parents. 30 patients will be asked to chew xylitol gum and the other 30 patients will refrain from chewing gum and serve as the control group. At the appointment for insertion of orthodontic appliances, patients will be instructed to chew one serving or two pieces of xylitol gum three times per day for a total of six grams of xylitol per day. Patients will participate in a survey at the following timepoints- 4 hours, 24 hours, 48 hours and 7 days. The expectation is that this study will determine the effectiveness of using xylitol to decrease pain in orthodontic patients.

Key Dates

Start date

Oct 31, 2025

Status verified

Sep 2025

Primary completion

Mar 31, 2026

Completion

Mar 31, 2026

Study Design

Enrollment

60 participants (estimated)

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Arms

• Active Comparator: Xylitol Gum
  Chew one serving or two pieces of xylitol gum three times per day for a total of six grams of xylitol per day.
• No Intervention: No Gum
  Control group that will refrain from chewing gum.

Primary Outcome Measure

Visual analogue scale Baseline [ Time Frame: Baseline ]

Central Contacts

• Peter Ngan, DMD
  304-293-3223
  [email protected]
• Karissa Spokane
  724-630-5624
  [email protected]

Locations (1)

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