Colonoscopic Detection of Phosphorylated Alpha-synuclein for Parkinson's Diagnosis

Part of paid clinical trials in Portland, Oregon.

Sponsor
CND Life Sciences
Study ID
NCT07204652
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
40 Years - 99 Years
Healthy Volunteers
Not accepted

Interventions

  • No Intervention: Observational Cohort — DIAGNOSTIC_TEST
    No Intervention: Observational Cohort

Study Details

The goal of this observational study is to learn whether tissue samples taken from the colon during routine colonoscopy can detect signs of Parkinson's disease. The main question it aims to answer is: Can doctors find a protein called alpha-synuclein in colon tissue samples from people with Parkinson's disease? Currently, Parkinson's disease is diagnosed by observing symptoms like tremors and movement problems, but by then the disease has already progressed significantly. Earlier detection could help doctors start treatment sooner.

Key Dates

Start date
Sep 3, 2025
Status verified
Feb 2026
Primary completion
Sep 30, 2028
Completion
Sep 30, 2029

Study Design

Enrollment
20 participants (estimated)

Primary Outcome Measure

Detection of phosphorylated alpha-synuclein in colon tissue samples [ Time Frame: At time of colonoscopy procedure ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Oregon Health & Science UniversityPortlandOregon97239
Magda Armendariz Sullivan
[email protected]
503-501-8478
Sarah Diamond, MD (SUB_INVESTIGATOR)

Find similar trials in Portland, OR

By condition
Parkinson's disease
By specialty
NeurologyBrain disorders
By research site
Oregon Health & Science University· Portland, OR

Related Studies