Evaluation of CT-XPI

Part of paid clinical trials in Madison, Wisconsin.

Sponsor: University of Wisconsin, Madison
Study ID: NCT07192133
Phase: PHASE2
Status: Recruiting

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Conditions

CT Scan
Computed Tomography

Eligibility Criteria

Sex: ALL
Age: 18 Years - N/A
Healthy Volunteers: Not accepted

Interventions

CT scan — DIAGNOSTIC_TEST
Dynamic contrast-free chest CT scan

Study Details

The goal of this clinical trial is to learn if a new computed tomography (CT) lung perfusion imaging method is as effective as standard of care (SOC) CT imaging. The main question it aims to answer is: * Does the new contrast-free method provide more information about lung perfusion than SOC? Participants will undergo a 30 minute chest CT.

Key Dates

Start date: Jan 26, 2026
Status verified: Jun 2026
Primary completion: Dec 31, 2026
Completion: Dec 31, 2026

Study Design

Enrollment: 30 participants (estimated)
Allocation: NA
Intervention model: SINGLE_GROUP
Primary purpose: DIAGNOSTIC

Arms

Experimental: CT scan
Participants undergoing a CT

Primary Outcome Measure

Lung x-ray pulsatility index (XPI) [ Time Frame: 30 minutes ]

Central Contacts

Radiology Studies
608-282-8349
[email protected]

Locations (1)

Facility	City	State	ZIP	Site coordinators
University of Wisconsin - Madison	Madison	Wisconsin	53705	Matthew Smith, MD, PhD (PRINCIPAL_INVESTIGATOR) Timothy Szczykutowicz, PhD (SUB_INVESTIGATOR)

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By research site

University of Wisconsin - Madison· Madison, WI