CMT Gait, Mobility, Balance - AOFAS Grant

Part of paid clinical trials in North Liberty, Iowa.

Sponsor
Bopha Chrea
Study ID
NCT07188415
Status
Recruiting
Apply to this trial

Conditions

  • Charcot Marie Tooth Disease (CMT)

Eligibility Criteria

Sex
ALL
Age
25 Years - 55 Years
Healthy Volunteers
Not accepted

Interventions

  • Ankle-foot Orthoses — DEVICE
    Group 1 will consist of individuals who have CMT and have undergone surgical correction (OP) and Group 2 will be AFO users who have CMT but have not undergone major surgical correction (NonOP).

Study Details

The overall objective of the proposed research is to begin to better understand the potential benefits and limitations of ankle -foot orthosis (AFO) use in the context of mobility and balance during gait for individuals with Charcot-Marie-Tooth disease (CMT). These benefits will be studied in comparison to those offered by surgical correction. We will accomplish by having subjects undergo mobility and balance tests in our gait analysis lab.

Key Dates

Start date
Aug 14, 2025
Status verified
Sep 2025
Primary completion
Aug 31, 2026
Completion
Jan 31, 2027

Study Design

Enrollment
66 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
OTHER

Arms

  • No Intervention: OP
    Charcot-Marie-Tooth patients who have undergone surgical correction but do not wear ankle-foot orthoses.
  • Other: NonOP
    Charcot-Marie-Tooth patients who have not undergone surgical correction, but do wear clinically prescribed ankle-foot orthoses. NonOP subjects will complete study procedures both with and without their AFOs.

Primary Outcome Measure

Four-Square Step Test [ Time Frame: Baseline ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Iowa Medical Campus - North Liberty (MCNL)North LibertyIowa52713
Bopha Chrea, MD
[email protected]
319-356-3943
Jason Wilken, PT, PhD
[email protected]

Find similar trials in North Liberty, IA

By research site
University of Iowa Medical Campus - North Liberty (MCNL)· North Liberty, IA

Related Studies