Organization and Development of Motor Cortical Circuits for Speech Production in Stuttering

Part of paid clinical trials in Ann Arbor, Michigan.

Sponsor
University of Michigan
Study ID
NCT07180628
Status
Recruiting
Apply to this trial

Conditions

  • Stutter
  • Stuttering
  • Stuttering, Adult
  • Stuttering, Developmental

Eligibility Criteria

Sex
ALL
Age
18 Years - 65 Years
Healthy Volunteers
Not accepted

Interventions

  • Speech Production During functional magnetic resonance imaging (MRI) — BEHAVIORAL
    Participants will complete a speech production task with 2 conditions (stuttered, non-stuttered) while undergoing functional MRI to assess brain activity. Brain activity will be compared within subjects for the 2 conditions. The intervention is the combination of tasks delivered to all participants. The speaking task is the intervention (modifying agent) and the MRI is a measurement tool, not a therapeutic or modifying agent.

Study Details

The overall objective of this study is to examine inter effector areas (IEAs) activity and functional connectivity during continuous speech production in stuttering adults.

Key Dates

Start date
Apr 24, 2026
Status verified
Apr 2026
Primary completion
Mar 31, 2029
Completion
Mar 31, 2029

Study Design

Enrollment
50 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: Stutter group
    Participants that stutter

Primary Outcome Measure

Blood-Oxygen-Level-Dependent (BOLD) signal change during speaking [ Time Frame: During the speech task (5 runs, 8 minutes each) distributed across MRI Visits 1-6, up to 12 months from enrollment. ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of MichiganAnn ArborMichigan48109
Emily Garnett, PhD
[email protected]
734-232-3371
Soo-Eun Chang, PhD (PRINCIPAL_INVESTIGATOR)

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By research site
University of Michigan· Ann Arbor, MI

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