Tailored Patient Navigation to Improve the Uptake of Lung Cancer Screening in Tribal Communities in Western Washington State, SACRED LUNGS Trial

Conditions

• Lung Carcinoma

Eligibility Criteria

Sex

ALL

Age

18 Years - N/A

Healthy Volunteers

Accepted

Interventions

• Patient Navigation — BEHAVIORAL
  Receive tailored PN activities
• Educational Intervention — OTHER
  Receive LCS educational handout
• Best Practice — OTHER
  Receive enhanced usual care
• Interview — OTHER
  Ancillary studies
• Survey Administration — OTHER
  Ancillary studies
• Electronic Health Record Review — OTHER
  Ancillary studies

Study Details

This clinical trial studies whether tailored patient navigation (PN) works to improve the uptake of lung cancer screening (LCS) in tribal communities in western Washington state. Lung cancer is the leading cause of cancer death in the United States among American Indian (AI) and Alaska Native (AN) people, and the incidence of lung cancer is higher in this population in the Northern and Southern Plains, Alaska, and Pacific Coast regions. In Washington state, AI/AN people also have twice the rate of commercial cigarette smoking than the overall population. LCS with annual low-dose chest computed tomography (CT) can reduce lung cancer death and is recommended in people 50-80 years of age with current or recent (within 15 years) tobacco use and a 20 pack-year or greater smoking history. Despite this, AI and AN people are less likely to receive LCS which may be due to barriers they face making it difficult to receive LCS. PN services are designed to guide a patient through the healthcare system and reduce barriers to timely screening, follow-up, diagnosis, treatment, and supportive care. The PN services in this trial have been tailored for the tribal communities in western Washington state. The services are designed to help participants overcome the unique barriers that their tribal communities face and improve the uptake of LCS.

Key Dates

Start date

Jul 1, 2026

Status verified

Feb 2026

Primary completion

Mar 29, 2029

Completion

Apr 30, 2029

Study Design

Enrollment

237 participants (estimated)

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SCREENING

Arms

• Experimental: Arm 1 (tailored PN)
  Participants receive tailored PN activities in support of the uptake and follow-up of LCS for 21 months. Participants also receive an educational handout on LCS on study.
• Active Comparator: Arm 2 (enhanced usual care, delayed tailored PN)
  Participants receive enhanced usual care consisting of an educational handout on LCS and a warm hand-off to discuss LCS with their PCP for 6 months. Participants then receive tailored PN services in support of the uptake and follow-up of LCS for 15 months.

Primary Outcome Measure

Completion of chest computed tomography (CT) (Aim 1.2) [ Time Frame: Up to 6 months ]

Central Contacts

• Matty Triplette, MD, MPH
  (206) 667-6335
  [email protected]

Locations (2)

Find similar trials in Auburn, WA

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