Rocklatan Retinal Perfusion OCT Study

Part of paid clinical trials in Portland, Oregon.

Sponsor
Oregon Health and Science University
Study ID
NCT07174401
Phase
PHASE4
Status
Not Yet Recruiting

Notify me when recruiting opens

Save your spot on the interest list for this study. We'll keep your details with this study so our team can follow up when recruiting opens.

Not yet recruiting

Add your contact details and location so we can keep your interest tied to this study.

Conditions

Eligibility Criteria

Sex
ALL
Age
21 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Rocklatan eye drops will be instilled nightly in one eye diagnosed with glaucoma for up to 12 months. — DRUG
    The eye not selected as the study eye will be used for comparison so both eyes will be imaged with the study devices to assess blood flow changes.
  • Two optical coherence tomography (OCT) devices will be used to assess blood flow changes. — DEVICE
    One OCT device is FDA-cleared while the other is still experimental. Both devices assess blood flow in different ways.

Study Details

The main purpose of this study is to learn more about how Rocklatan eye drops affects blood flow in the eye. The secondary purpose is to see if our study devices can detect changes in blood flow before and after instillation of Rocklatan.

Key Dates

Start date
Jan 31, 2026
Status verified
Dec 2025
Primary completion
Dec 31, 2026
Completion
Oct 31, 2027

Study Design

Enrollment
30 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Eye with Diagnosed Glaucoma
  • No Intervention: Control Eye
    This is also an eye with glaucoma, but the control eye will use clinically prescribed medication instead of the study drug.

Primary Outcome Measure

Nerve Fiber Layer Plexus Capillary Density (NFLP CD) [ Time Frame: From enrollment to end of treatment at 11-12 months ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Casey Eye Institute - Oregon Health & Science UniversityPortlandOregon97239
Chinmay Deshpande, MS Optom
[email protected]
503-494-9628
Denzil Romfh, OD
[email protected]
503-494-4351
Michael Gale, MD (SUB_INVESTIGATOR)
Aiyin Chen, MD (SUB_INVESTIGATOR)
Eliesa Ing, MD (SUB_INVESTIGATOR)
Ou Tan, PhD (SUB_INVESTIGATOR)
Yali Jia, PhD (SUB_INVESTIGATOR)

Find similar trials in Portland, OR

By condition
Glaucoma
By specialty
Ophthalmology
By research site
Casey Eye Institute - Oregon Health & Science University· Portland, OR

Related Studies