Post-stroke Pain tAN-fMRI

Conditions

• Post Stroke Pain

Eligibility Criteria

Sex

ALL

Age

18 Years - 80 Years

Healthy Volunteers

Not accepted

Interventions

• Transcutaneous Auricular Neurostimulation — DEVICE
  Transcutaneous Auricular Neurostimulation (tAN) is a wearable, electrical stimulation device that delivers electricity to specific parts of the human ear.

Study Details

The purpose of this study is to explore whether 4 weeks of at-home transcutaneous auricular neurostimulation (tAN) can reduce chronic pain after a stroke. Investigators will recruit up to 24 participants with chronic post-stroke upper extremity pain. The goal is to determine if there is a pain reduction after ear stimulation.

Key Dates

Start date

Jan 8, 2026

Status verified

Feb 2026

Primary completion

Jun 30, 2027

Completion

Jun 30, 2027

Study Design

Enrollment

24 participants (estimated)

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Arms

• Experimental: 2 Weeks Sham tAN followed by 2 Weeks Active tAN
  Participants will be randomized to receive 2 weeks of at-home, self-administered sham Transcutaneous Auricular Neurostimulation (tAN), followed by 2 weeks of at-home, self-administered active Transcutaneous Auricular Neurostimulation (tAN).
• Experimental: Four Weeks of Active Transcutaneous Auricular Neurostimulation
  Participants will be randomized to receive 2 weeks of at-home, self-administered active Transcutaneous Auricular Neurostimulation (tAN), followed by 2 additional weeks of at-home, self-administered active Transcutaneous Auricular Neurostimulation (tAN).

Primary Outcome Measure

Sensory Threshold [ Time Frame: 4 weeks ]

Central Contacts

• Institutional RBFHR Recruitment Contact
  843-792-9502
  [email protected]

Locations (2)

Find similar trials in Charleston, SC

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