Partial Pleurectomy (Surgery) for Unresectable Pleural Mesothelioma

Part of paid clinical trials in Chicago, Illinois.

Sponsor
University of Chicago
Study ID
NCT07126509
Status
Recruiting
Apply to this trial

Conditions

  • Mesothelioma
  • Mesothelioma Malignant Advanced
  • Mesothelioma, Malignant
  • Mesothelioma; Lung
  • Mesotheliomas Pleural

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Partial Pleurectomy — PROCEDURE
    A partial pleurectomy is a surgical procedure where part of the pleura, the lining of the lung cavity, is removed. This may be done to remove tumors, excess tissue, or to treat lung complications.

Study Details

Purpose of the study: The main purpose of this research study is to see if a surgery procedure (limited partial pleurectomy and decortication) helps symptoms in people who have cancer that is unresectable that might not be able to be removed completely. This is called unresectable cancer. This study will also help the research team learn more about the types of symptoms and quality of life for people who have undergone this surgery, the number of complications following , and the time from surgery to starting other therapy. Th e study team also wants to see see the overall survival of people who have had this procedure as part of their care. What will be done as part of research on this study: * Surgery (Partial Pleurectomy - surgery to remove lining of lungs) * The research team will also ask study participants questions about their symptoms through questionnaires at certain times after surgery. How long this study will last: Participation in this research (pre-surgery, surgery and follow-up) will last for about 2 years. Confidentiality: All personal information will be kept confidential, and data will be used only for research purposes. Contact Information: For more information about this study, please contact [email protected]

Key Dates

Start date
Dec 2, 2025
Status verified
Feb 2026
Primary completion
Dec 1, 2028
Completion
Dec 1, 2028

Study Design

Enrollment
30 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: All Study Participants
    This study arm will include all study participants receiving a partial pleurectomy (Surgery) for unresectable pleural mesothelioma. Participants in this study arm will all receive the same study procedures.

Primary Outcome Measure

Disease-related Symptom Burden 3 Months After Partial Pleurectomy (Surgery) [ Time Frame: 3 months after surgery ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Chicago Medicine Comprehensive Cancer CenterChicagoIllinois60637
Cancer Trial Intake
[email protected]
855-702-8222
Darren Bryan, MD (PRINCIPAL_INVESTIGATOR)

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By research site
University of Chicago Medicine Comprehensive Cancer Center· Chicago, IL

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