Lactated Ringer's and Dextrose 5% vs Only Lactated Ringer's in Labor

Conditions

• Induced Labor

Eligibility Criteria

Sex

FEMALE

Age

18 Years - N/A

Healthy Volunteers

Not accepted

Interventions

• 5% Dextrose (D5) in Normal Saline (NS) — DRUG
  A solution of 5% dextrose and lactate ringer will be given to one group of participants.
• Lactate Ringer — DRUG
  A Lactate Ringer solution will be given to one group of participants.

Study Details

The goal of this clinical trial is to determine which of two types of standard intravenous (IV) fluids (a combination of 5% dextrose and Lactated Ringers solution and Lactated Ringers solution alone) has a better influence on labor when inducing labor in pregnant women. The main questions it aims to answer are: 1. Does the use of 5% dextrose and Lactated Ringers lead to a shorter labor than the use of just Lactated Ringers? 2. Does the use of 5% dextrose and Lactated Ringers increase the risk of neonatal hypoglycemia when compared to Lactated Ringers? Participants in this trial will be randomly assigned to one of two groups: a group that receives a solution of 5% dextrose and Lactated Ringers, and a group that receives Lactated Ringers alone. Researchers will compare the outcomes of the two groups to see which IV fluid is more effective.

Key Dates

Start date

Sep 30, 2025

Status verified

Aug 2025

Primary completion

Mar 31, 2026

Completion

Mar 31, 2026

Study Design

Enrollment

158 participants (estimated)

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Arms

• Active Comparator: 5% dextrose and Lactate Ringer
  Participants randomized to this arm will receive an intravenous solution of 5% dextrose and Lactate Ringer during labor.
• Active Comparator: Lactate Ringer only
  Participants randomized to this arm will receive an intravenous Lactate Ringer solution only.

Primary Outcome Measure

Time from Induction Start To Delivery [ Time Frame: From enrollment to the end of labor ]

Central Contacts

• Tetsuya Kawakita, MD
  757-446-7900
  [email protected]

Locations (1)

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