Definitive Radiation Therapy for Inoperable Breast Cancer

Part of paid clinical trials in Stony Brook, New York.

Sponsor
Alexander Stessin
Study ID
NCT07122713
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
FEMALE
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Whole breast radiation with simultaneous integrated boost (WB-SIB) to primary breast tumor — RADIATION
    Radiation with 26Gy to the whole breast and 40Gy simultaneous integrated boost to gross disease in the breast, in five fractions
  • Whole breast radiation with simultaneous integrated boost (WB-SIB) to primary breast tumor and ipsilateral axillary lymph nodes — RADIATION
    Radiation with 26Gy to the whole breast and regional nodes with a 40Gy simultaneous integrated boost to gross disease in breast and ipsilateral axillary nodal areas, in five fractions

Study Details

The purpose of this study is to find out if adding radiation therapy to routine medications for breast cancer helps in reducing and preventing the cancer from getting worse. Patients with a locally advanced breast cancer who cannot, or do not want to, undergo surgery are eligible to participate. Participation in this study does not prevent you from undergoing surgery in the future.

Key Dates

Start date
Dec 8, 2025
Status verified
Dec 2025
Primary completion
Dec 30, 2028
Completion
Dec 30, 2033

Study Design

Enrollment
30 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: A: Ipsilateral axillary node-negative breast cancer
    Patients with ipsilateral axillary lymph node-negative disease, regardless of metastatic status (Stages T1-4 N0 M0-1)
  • Experimental: B: Ipsilateral axillary node-positive breast cancer
    Patients with ipsilateral axillary node-positive disease, regardless of metastatic status (Stages T1-4 N1-2 M0-1)

Primary Outcome Measure

Treatment Safety [ Time Frame: 12 months ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Stony Brook University Cancer CenterStony BrookNew York11794
Cancer Clinical Trials Office
[email protected]
(631)-728-7425
[email protected]
Alexander Stessin, MD PhD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Stony Brook, NY

By condition
Breast cancer
By specialty
OncologyBreast oncologyWomen's health
By research site
Stony Brook University Cancer Center· Stony Brook, NY

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