Effects of Pomegranate Juice on Ulcerative Colitis

Part of paid clinical trials in Los Angeles, California.

Sponsor
University of California, Los Angeles
Study ID
NCT07115862
Status
Recruiting
Apply to this trial

Conditions

  • Ulcerative Colitis (Disorder)

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • pomegranate juice -> habitual diet — OTHER
    237 ml of pomegranate juice for the first 8 weeks -\> habitual diet for the second 8 weeks
  • habitual diet -> pomegranate juice — OTHER
    habitual diet for the first 8 weeks -\> 237 ml of pomegranate juice for the second 8 weeks

Study Details

The purpose of this study is to determine whether consumption of 237 ml of pomegranate juice daily for 8 weeks will: 1. lower inflammation (in the gut as well as generally in the body) and improve your overall quality of life 2. affect the microbes living in the gut (gut microbiota)

Key Dates

Start date
Oct 15, 2025
Status verified
Aug 2025
Primary completion
Oct 15, 2027
Completion
Oct 15, 2027

Study Design

Enrollment
30 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
SUPPORTIVE_CARE

Arms

  • Experimental: Intervention
    Participants in this arm will be consuming 237 ml of pomegranate juice for the first 8 weeks of the study and their habitual diet without pomegranate juice for the second 8 weeks
  • Experimental: Delayed start
    Participants in this arm will consume their habitual diet for the first 8 weeks of the study and drink 237 ml of pomegranate juice for the second 8 weeks

Primary Outcome Measure

simple clinical colitis activity index (SCCAI) [ Time Frame: At baseline, 8 weeks and 16 weeks ]

Central Contacts

Locations (2)

FacilityCityStateZIPSite coordinators
UCLA Center for Human NutritionLos AngelesCalifornia90095
Tatiana Diacova, PhD, MS, RD
[email protected]
310-206-8292
Zhaoping Li, MD, PhD (PRINCIPAL_INVESTIGATOR)
Berkeley Limketkai, MD, PhD (SUB_INVESTIGATOR)
West Los Angeles VA Medical CenterLos AngelesCalifornia90073
Tatiana Diacova, PhD, MS, RD
[email protected]
310-206-8292
Zhaoping Li, MD, PhD (PRINCIPAL_INVESTIGATOR)

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UCLA Center for Human Nutrition· Los Angeles, CAWest Los Angeles VA Medical Center· Los Angeles, CA