Study to Evaluate Subcutaneous (SC) VGA039 in Patients With Von Willebrand Disease (VWD)

Part of paid clinical trials in Little Rock, Arkansas.

Sponsor
Vega Therapeutics, Inc
Study ID
NCT07115004
Phase
PHASE3
Status
Recruiting
Apply to this trial

Conditions

  • Von Willebrand Disease (VWD)

Eligibility Criteria

Sex
ALL
Age
12 Years - 75 Years
Healthy Volunteers
Not accepted

Interventions

  • VGA039 — DRUG
    VGA039 SC administered for 49-weeks during the interventional phase following a 24-week observational period.

Study Details

This is a phase 3 study that will evaluate subcutaneous (SC) VGA039 in patients with von Willebrand Disease (VWD)

Key Dates

Start date
Oct 15, 2025
Status verified
Apr 2026
Primary completion
Oct 31, 2028
Completion
Oct 31, 2028

Study Design

Enrollment
60 participants (estimated)
Allocation
NA
Intervention model
SEQUENTIAL
Primary purpose
TREATMENT

Arms

  • Experimental: Multiple Doses of VGA039 after observational run-in
    Participants who meet eligibility criteria and complete a 24-week observational phase will receive VGA039 SC for approximately 49 weeks.

Primary Outcome Measure

Incidence of bleeding events [Efficacy] [ Time Frame: Time Frame: From 7 days after informed consent until 49 weeks after SC study drug initiation ]

Central Contacts

Locations (11)

FacilityCityStateZIPSite coordinators
Arkansas Children's HospitalLittle RockArkansas72202-
Luskin Orthopaedic Institute For ChildrenLos AngelesCalifornia90007-
UC Davis Medical CenterSacramentoCalifornia95817-
University of California San FranciscoSan FranciscoCalifornia94143-
Children's Healthcare of AtlantaAtlantaGeorgia30329-
Emory University HospitalAtlantaGeorgia30308
Emory University Hospital
(404) 686-0277
University of MinnesotaMinneapolisMinnesota55455-
Science 37, Inc. (Virtual Clinical MetaSite)MorrisvilleNorth Carolina27560
Science 37 Recruitment Team
[email protected]
1-855-737-3711
Hemophilia Center of Western PAPittsburghPennsylvania15213-
UT Southwestern Children's HospitalDallasTexas75235-
Washington Center for Bleeding DisordersSeattleWashington98101

Find similar trials in Little Rock, AR

By research site
Arkansas Children's Hospital· Little Rock, ARLuskin Orthopaedic Institute For Children· Los Angeles, CAUC Davis Medical Center· Sacramento, CAUniversity of California San Francisco· San Francisco, CAChildren's Healthcare of Atlanta· Atlanta, GAEmory University Hospital· Atlanta, GA

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