Multiple Dose Study of MK-2828 in Participants With Type 2 Diabetes (MK-2828-003)

Part of paid clinical trials in Chula Vista, California.

Sponsor
Merck Sharp & Dohme LLC
Study ID
NCT07089784
Phase
PHASE1
Status
Completed

Conditions

Eligibility Criteria

Sex
ALL
Age
24 Years - 75 Years
Healthy Volunteers
Not accepted

Interventions

  • MK-2828 — DRUG
    Oral capsule of MK-2828 taken once per day for 28 days.
  • Placebo — DRUG
    Placebo to match MK-2828 oral capsule, taken once per day for 28 days.

Study Details

The purpose of this study is to learn about the safety and if people tolerate a study medicine called MK-2828. The study will also measure what happens to MK-2828 in the body of a person with type 2 diabetes (T2D) over time (pharmacokinetic or PK study), and how it affects the amount of high-sensitivity C-reactive protein (hsCRP) in a person's blood.

Key Dates

Start date
Sep 22, 2025
Status verified
May 2026
Primary completion
May 4, 2026
Completion
May 4, 2026

Study Design

Enrollment
46 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: MK-2828
    Participants receive daily MK-2828 for 28 days.
  • Placebo Comparator: Placebo
    Participants receive daily placebo for 28 days.

Primary Outcome Measure

Number of Participants Who Experience an Adverse Event (AE) [ Time Frame: Up to approximately 42 days ]

Locations (11)

FacilityCityStateZIPSite coordinators
ProSciento Inc. ( Site 0004)Chula VistaCalifornia91911-
California Clinical Trials Medical Group managed by PAREXEL ( Site 0008)GlendaleCalifornia91206-
Velocity Clinical Research, Hallandale Beach ( Site 0010)HallandaleFlorida33009-
Jacksonville Center for Clinical Research ( Site 0002)JacksonvilleFlorida32216-
Advanced Pharma CR, LLC ( Site 0001)MiamiFlorida33147-
QPS Miami Research Associates ( Site 0005)South MiamiFlorida33143-
AMR Lexington ( Site 0012)LexingtonKentucky40509-
Alliance for Multispecialty Research, LLC ( Site 0013)Kansas CityMissouri64114-
Bio-Kinetic Clinical Applications, LLC dba QPS-MO ( Site 0009)SpringfieldMissouri65802-
AMR Clinical ( Site 0003)KnoxvilleTennessee37920-
ICON Early Phase Services ( Site 0006)San AntonioTexas78209-

Find similar trials in Chula Vista, CA

By condition
Type 2 diabetes
By specialty
EndocrinologyMetabolic healthWeight loss
By research site
ProSciento Inc.· Chula Vista, CACalifornia Clinical Trials Medical Group managed by PAREXEL· Glendale, CAVelocity Clinical Research, Hallandale Beach· Hallandale, FLJacksonville Center for Clinical Research· Jacksonville, FLAdvanced Pharma CR, LLC· Miami, FLQPS Miami Research Associates· South Miami, FL

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