The Acute Effects of Psilocybin on Cognition, Memory, and Brain Function

Part of paid clinical trials in Austin, Texas.

Sponsor
Manoj Doss
Study ID
NCT07079852
Phase
PHASE1/PHASE2
Status
Not Yet Recruiting

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Conditions

  • Healthy

Eligibility Criteria

Sex
ALL
Age
21 Years - 45 Years
Healthy Volunteers
Accepted

Interventions

  • Placebo — DRUG
    This is an inactive control condition.
  • Psilocybin 15mg — DRUG
    This is a moderate psychoactive dose.

Study Details

This study will test the effects of psilocybin on memory and cognition in healthy participants using computerized tasks and magnetic resonance imaging (MRI).

Key Dates

Start date
Sep 30, 2025
Status verified
Jul 2025
Primary completion
Aug 31, 2027
Completion
Aug 31, 2027

Study Design

Enrollment
48 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE

Arms

  • Placebo Comparator: placebo
    Capsule containing microcrystalline cellulose
  • Experimental: psilocybin
    Capsule containing 15 mg of psilocybin

Primary Outcome Measure

Memory accuracy from performance on a recognition memory test [ Time Frame: 8 weeks ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
The University of Texas at Austin Dell Medical SchoolAustinTexas78712
Manoj Doss, PhD
[email protected]
512-495-5856
Manoj Doss, PhD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Austin, TX

By research site
The University of Texas at Austin Dell Medical School· Austin, TX

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