Quantification & Classification of Inflammatory Cells in Uveitis Using OCT

Part of paid clinical trials in Portland, Oregon.

Sponsor
Oregon Health and Science University
Study ID
NCT07065747
Status
Recruiting
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Conditions

  • Anterior Uveitis (AU)
  • Behcet Disease
  • Birdshot Chorioretinitis
  • Herpes Simplex Virus
  • Juvenile Idiopathic Arthritis (JIA)
  • Posterior Vitreous Detachment
  • Sarcoidosis
  • Spondyloarthritis (SA)

Eligibility Criteria

Sex
ALL
Age
5 Years - 85 Years
Healthy Volunteers
Accepted

Study Details

The goal of this study is to determine if it's possible to use a high resolution imaging device called optical coherence tomography (OCT) to develop an unbiased, standard method of counting and categorizing the various types of cells and proteins found in an eye condition called anterior uveitis. Anterior uveitis is a type of inflammation in the eye that can be caused by many different diseases of the body.

Key Dates

Start date
Sep 1, 2024
Status verified
Jul 2025
Primary completion
Sep 30, 2026
Completion
Dec 31, 2026

Study Design

Enrollment
125 participants (estimated)

Arms

  • Arm: Uveitis Group
    Eyes with active inflammation due to various systemic diseases
  • Arm: Posterior Vitreous Detachment Group
    Eyes with vitreous floaters and posterior vitreous detachment
  • Arm: Healthy/Control Group
    Healthy eyes with no history of uveitis, posterior vitreous detachment, or previous eye surgery

Primary Outcome Measure

Identification & Measurement of Anterior Chamber Cells [ Time Frame: Day 1 ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Casey Eye Institute - Oregon Health & Science UniversityPortlandOregon97239-

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Casey Eye Institute - Oregon Health & Science University· Portland, OR

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