Combined Effect of Aerobic and Resistance Exercise in Non Ischemic Dilated Cardiomyopathy Patients

Sponsor
Riphah International University
Study ID
NCT07062874
Status
Not Yet Recruiting

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Conditions

Eligibility Criteria

Sex
ALL
Age
40 Years - 60 Years
Healthy Volunteers
Not accepted

Interventions

  • Combined Aerobic and Resistance Exercise — BEHAVIORAL
    Participants received supervised exercise training 3 times per week for 6 weeks. Each session included a 10-minute warm-up (walking at 1.5 km/h), a 30-minute aerobic phase at 60-85% heart rate reserve (calculated using the Karvonen formula), and a 10-minute cool-down (walking at 1 km/h). In addition, participants performed resistance training for upper and lower extremities using TheraBands, with 8-10 sets targeting major muscle groups.
  • Aerobic Exercise Only — BEHAVIORAL
    Participants followed the same aerobic training protocol as the experimental group-3 sessions per week for 6 weeks, with 10-minute warm-up, 30-minute aerobic exercise (60-85% HRR), and 10-minute cool-down. No resistance training was provided.

Study Details

This study explores the effects of combined aerobic and resistance exercise in patients with non-ischemic dilated cardiomyopathy (NIDCM). In a six-week randomized clinical trial with 66 participants, both exercise groups-combined and aerobic-only-showed significant improvements in exercise capacity, functional independence, dyspnea, and blood pressure. However, no significant difference was found between the two groups. The study concludes that both exercise approaches are effective, but longer studies are needed to determine if combined training offers added benefits.

Key Dates

Start date
Jul 28, 2025
Status verified
Jul 2025
Primary completion
Sep 28, 2025
Completion
Oct 10, 2025

Study Design

Enrollment
66 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Combined Aerobic and Resistance Exercise:
    Participants performed aerobic training three times a week for six weeks. Each session included a 10-minute warm-up, 30-minute main aerobic activity (60-85% of heart rate reserve using the Karvonen formula), and 10-minute cool-down. Additionally, they performed resistance exercises for upper and lower extremities using TheraBands, 8-10 sets covering major muscle groups, three times a week.
  • Active Comparator: Aerobic Exercise Only
    Participants followed the same aerobic training protocol as Group A. No resistance training was included. Sessions also occurred three times a week for six weeks, with similar warm-up, active, and cool-down phases.

Primary Outcome Measure

Functional Independence Measure (FIM) questionnaire [ Time Frame: Baseline and 6 weeks ]

Central Contacts

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