Combined Amivantamab, Carboplatin and Paclitaxel in Unresectable Locally Recurrent or Metastatic Head and Neck Cancer
Part of paid clinical trials in Tucson, Arizona.
- Sponsor
- SWOG Cancer Research Network
- Study ID
- NCT07062354
- Phase
- PHASE2
- Status
- Enrolling By Invitation
Conditions
- Head &Amp; Neck Cancer
- Head &Amp; Neck Squamous Cell Carcinoma
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - N/A
- Healthy Volunteers
- Not accepted
Interventions
- Amivantamab Subcutaneous and Co-Formulated with Recombinant Human Hyaluronidase (SC CF) — DRUGCarboplatin + Paclitaxel + Amivantamab hyaluronidase
Study Details
This research study is for people who have head and neck cancer that has come back or spread to other places in the body.
Key Dates
- Start date
- Mar 25, 2026
- Status verified
- May 2026
- Primary completion
- Oct 31, 2028
- Completion
- Oct 31, 2029
Study Design
- Enrollment
- 50 participants (estimated)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Other: Participants with unresectable recurrent or metastatic HNSCCCarboplatin + Paclitaxel + Amivantamab hyaluronidase
Primary Outcome Measure
Overall Response Rate [ Time Frame: Up to 2 years after registration ]
Locations (3)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| University of Arizona Cancer Center | Tucson | Arizona | 85719 | - |
| University of Michigan Rogel Cancer Center | Ann Arbor | Michigan | 48109 | - |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | - |
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