The Study of Urinary Biomarkers in Patients With Hypomagnesemia
Part of paid clinical trials in Gainesville, Florida.
- Sponsor
- University of Florida
- Study ID
- NCT07056283
- Status
- Recruiting
Conditions
- Hypomagnesemia
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - 99 Years
- Healthy Volunteers
- Not accepted
Study Details
In this pilot exploratory study, we aim to examine extracellular vesicles (EVs) as biomarkers in urine from up to 15 patients, with up to 10 samples per patient among the patients with a history of hypomagnesemia.
Key Dates
- Start date
- Jul 31, 2025
- Status verified
- Aug 2025
- Primary completion
- Jun 30, 2027
- Completion
- Jun 30, 2027
Study Design
- Enrollment
- 15 participants (estimated)
Arms
- Arm: Hypomagnesemia (serum Mg <1.7 mg/dL)The patients will be selected with a history of hypomagnesemia. The urine samples will be collected at various intervals depending on the most recent serum magnesium levels available during the study period. The patients may or may not be on medications known to alter serum magnesium levels.
Primary Outcome Measure
Changes in urinary markers pNKCC2/NKCC2, pNCC/NCC, pSPAK/SPAK, uEGF/Cr, TRPM6, Uromodulin [ Time Frame: 2 years ]
Central Contacts
- Chintan Shah, MD(352) 294-8790
Locations (1)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| University of Florida | Gainesville | Florida | 32610 | Chintan Shah, MD (PRINCIPAL_INVESTIGATOR) |
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