Contrast Enhanced Ultrasound in Neurosurgery to Improve Glioma Visualization and Border Demarcation

Part of paid clinical trials in Aurora, Colorado.

Sponsor
University of Colorado, Denver
Study ID
NCT07050836
Phase
EARLY_PHASE1
Status
Recruiting
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Conditions

  • Glioma
  • Glioma (Any Grade) in the Brain

Eligibility Criteria

Sex
ALL
Age
18 Years - 95 Years
Healthy Volunteers
Not accepted

Interventions

  • Definity contrast during ultrasound — COMBINATION_PRODUCT
    Definity contrast injection given just prior to brain tumor surgery. Contrast enhanced ultrasound during brain tumor surgical resection to aid in brain tumor visualization.

Study Details

This study plans to learn more about using contrast enhanced ultrasound (CEUS) in brain tumor surgery. The goal of glioma brain tumor surgery is to remove as much of the glioma as possible. Tumor tissue that is close to normal brain tissue can look very similar. This can make it difficult for the surgeon to remove all the tumor. In this study, we hope to learn if using CEUS during brain tumor surgery will allow the brain surgeon to better see and remove all the tumor tissue.

Key Dates

Start date
Dec 5, 2025
Status verified
Feb 2026
Primary completion
Dec 31, 2026
Completion
Jun 30, 2027

Study Design

Enrollment
100 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER

Arms

  • Experimental: Brain tumor surgery with Definity contrast and Contrast Enhanced Ultrasound

Primary Outcome Measure

Primary Objective [ Time Frame: Up to 3 days ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Colorado Anschutz Medical CampusAuroraColorado80045
Jennifer Maitlen, BSN
[email protected]
303-724-1995
Terra Ornelas, BSN
[email protected]
303-724-7970
D. Ryan Ormond, MD PhD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Aurora, CO

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Brain cancer
By specialty
OncologyNeuro-oncology
By research site
University of Colorado Anschutz Medical Campus· Aurora, CO

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