Shortened Course of Radiation Therapy After Trans-oral Robotic Surgery in Patients With HPV-Mediated Oropharyngeal Squamous Cell Carcinoma.

Part of paid clinical trials in Salt Lake City, Utah.

Sponsor
University of Utah
Study ID
NCT07044635
Phase
PHASE2
Status
Recruiting
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Conditions

  • HPV-mediated Oropharyngeal Squamous Cell Carcinoma
  • Oropharyngeal Squamous Cell Carcinoma

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Radiation Therapy — RADIATION
    Reduced dose and Hypofractionated radiation therapy

Study Details

The goal of this study is to evaluate if a shorter course of therapy can improve the quality of life in patients receiving radiation therapy after trans-oral robotic surgery.

Key Dates

Start date
Jul 23, 2025
Status verified
Feb 2026
Primary completion
Aug 31, 2029
Completion
Aug 31, 2030

Study Design

Enrollment
42 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: 10 fractions of radiation therapy
  • Active Comparator: Radiation therapy with chemotherapy, if applicable, per standard of care

Primary Outcome Measure

Stable or improved FACT-HN at 6 months post-treatment compared to baseline. [ Time Frame: 2 years ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Huntsman Cancer Institute/University of UtahSalt Lake CityUtah84112
Rachel Kingsford
[email protected]
801-585-0115
Shane Lloyd
[email protected]
801-585-0255

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By research site
Huntsman Cancer Institute/University of Utah· Salt Lake City, UT

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