Short-term Effects of Caffeine and a Multi-ingredient Pre-workout on Exercise Performance

Part of paid clinical trials in St Louis, Missouri.

Sponsor
St. Louis University
Study ID
NCT07024940
Status
Recruiting

Conditions

  • Anthocyanins
  • Coffee
  • Exercise Performance

Eligibility Criteria

Sex
ALL
Age
18 Years - 35 Years
Healthy Volunteers
Accepted

Interventions

  • Ethiopian Coffee — OTHER
    Ethiopian Coffee is used as a real-world example of one of the most common drinks in the world.
  • Supplement — DIETARY_SUPPLEMENT
    A pre-workout supplement that contains anthocyanins and caffeine as ergogenic aids
  • Water (Placebo) — OTHER
    Bottled water acting as the placebo

Study Details

The investigators are conducting a study to see how a commercial pre-workout supplement, coffee, and water affect how well people perform. The study is conducted across four visits. The first visit is to assess the participants, and the next three visits are for testing. Each participant will drink a randomly assigned beverage 45 minutes before testing. Throughout the study, the participants will complete three testing days-each at least three days apart-so they can try all three drinks. The first test is the Wingate test, where the participants pedal as fast as they can for 30 seconds against a set resistance. The second test is a 1-mile treadmill run/walk on an incline, where the participant tries to complete the distance as fast as possible. The third test measures reaction time using light-up buttons to see how quickly a participant responds by touching them. These tests will help determine if any of the drinks improve performance. The results can help people choose the best drink for their workouts or races.

Key Dates

Start date
Apr 25, 2025
Status verified
Jun 2025
Primary completion
Aug 1, 2026
Completion
Sep 1, 2026

Study Design

Enrollment
12 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
OTHER

Arms

  • Experimental: Ethiopian Coffee
    A light roast Ethiopian Coffee is used based on previous research using the same technique for brewing. The coffee is brewed using the Aeropress coffee maker and the Timemore C3Pro hand grinder to grind the coffee. The recipe uses 15 grams of ground coffee set at the same grind setting (16 clicks) and 200 grams of water to have a target cup size of 175 mL plus 50 grams of ice to rapidly cool down the drink for consumption.
  • Experimental: Anthocyanin-Caffeine
    An anthocyanin-caffeine pre-workout supplement containing 120 mg of anthocyanins from New Zealand Blackcurrant berries, along with 120 mg of caffeine. This single-serve packet is stirred into 8 ounces of water and served.
  • Placebo Comparator: Water
    Water used as a constant water intake across all three arms

Primary Outcome Measure

Change in anaerobic power measured by a 30-second all-out effort on a cycle ergometer [ Time Frame: At 45 minutes post-dose for each intervention condition ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Saint Louis UniversitySt LouisMissouri63103
Hossein Rafiei, PhD
314-977-8675
Dylan Moffatt, BSc (SUB_INVESTIGATOR)

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