Hemodynamics After Resistance Training

Part of paid clinical trials in Ann Arbor, Michigan.

Sponsor
University of Michigan
Study ID
NCT07022340
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
FEMALE
Age
40 Years - 60 Years
Healthy Volunteers
Not accepted

Interventions

  • Resistance Training Intervention — BEHAVIORAL
    Participants will complete a brief aerobic warm-up and dynamic stretching prior to each strength training session. Participants will complete 9 exercises for all major muscle groups. Strength testing at the baseline study visit will be used to determine initial load. Participants will complete 1 set of moderate-intensity loads (\~50% maximum and \~12 repetitions) in week 1, 2 sets in week 2, and 3 sets in week 3. By week 4, participants will be completing 3 sets at 60% of maximum. Weight loads will be progressively increased so volitional fatigue is reached by 8-12 repetitions/set.

Study Details

Women's blood vessel health gets worse after menopause, or "the change of life". Some women exercise less during menopause. Exercise can improve blood vessel health. The investigators want to know if resistance exercise, like lifting weights, can improve blood vessel health in women who are just starting menopause. The investigators also want to know if lifting weights can improve mood, sleep, and quality of life in women going through menopause. The investigators will have two groups of women for this study. One group will lift weights (do resistance exercise) twice per week, and the other group will get emails with information about menopause. The investigators will measure blood vessel health, sleep, mood, and menopause symptoms at the start and the end of this study and compare women who did and did not exercise.

Key Dates

Start date
Jun 6, 2025
Status verified
Jul 2025
Primary completion
Mar 31, 2026
Completion
Mar 31, 2026

Study Design

Enrollment
50 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION

Arms

  • Experimental: Resistance Training Intervention
    Participants randomized to resistance training will complete two sessions/week for 16 weeks.
  • No Intervention: Health Education Intervention
    Participants randomized to the health education control group will receive weekly emails with general menopause information. They will be instructed to maintain current lifestyle habits, including exercise habits while enrolled in this study. They will be provided with a personalized resistance training program, equipment orientation/training session, and a counseling phone call with an exercise physiologist following study completion, or they can re-enroll in the resistance training intervention after completing the control portion of the study.

Primary Outcome Measure

Vascular function [ Time Frame: At baseline and the end of the 16 week study period ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Michigan School of KinesiologyAnn ArborMichigan48109
Marnie K. McLean, M.S.
[email protected]
734-615-1711
Abbi D. Lane, Ph.D.
[email protected]
734-647-3843
Marnie K. McLean, M.S. (PRINCIPAL_INVESTIGATOR)

Find similar trials in Ann Arbor, MI

By condition
Menopause
By specialty
Women's healthFertility
By research site
University of Michigan School of Kinesiology· Ann Arbor, MI

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