Prospective Randomized Observer Blinded Single Center Study Comparing 90-day Functional Outcome in Patients Who Received Intravenous Propofol Infusion Versus Inhalational Sevoflurane for General Anesthesia During Mechanical Thrombectomy in Patients Who Suffered From Acute Ischemic Stroke

Conditions

• Acute Ischemic Stroke Patients

Eligibility Criteria

Sex

ALL

Age

18 Years - N/A

Healthy Volunteers

Not accepted

Interventions

• Anesthesia drugs during the surgery — PROCEDURE
  During treatment for acute ischemic stroke, patients will be given either inhalation or intravenous anesthesia.

Study Details

This study is being done to compare outcomes after surgery for individuals who receive anesthesia through by inhaling medication and individuals who receive anesthesia intravenously by needle when experiencing treatment for their stroke. Currently very little is known about the outcomes for patients when comparing these two techniques of providing anesthesia during surgery. This study will provide information regarding outcomes that will help health care providers decide which technique will be better for patients

Key Dates

Start date

Jun 4, 2025

Status verified

Mar 2026

Primary completion

May 31, 2027

Completion

Dec 31, 2027

Study Design

Enrollment

120 participants (estimated)

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Arms

• Active Comparator: inhalational sevoflurane
  When treated for acute ischemic stroke, patient will receive inhalation sevoflurane as anesthesia
• Active Comparator: intravenous propofol infusion
  When treated for acute ischemic stroke, patient will receive intravenous propofol infusion as anesthesia

Primary Outcome Measure

Functional Independence at 90 days [ Time Frame: From enrollment to 90 days after treatment ]

Central Contacts

• Arun George, MD
  913-588-6670
  [email protected]

Locations (1)

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