Sodium in the Skin and Atopic Dermatitis

Part of paid clinical trials in San Francisco, California.

Sponsor
University of California, San Francisco
Study ID
NCT06998446
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
50 Years - N/A
Healthy Volunteers
Accepted

Study Details

The goal of this observational study is to understand factors associated with skin sodium storage in healthy adults and people with atopic dermatitis ages 50 and above. The study is designed to test whether diet and skin barrier function are associated with skin sodium concentration and whether skin sodium concentration is linked to atopic dermatitis and immune profiles over time. Participants will be asked to complete questionnaires, provide bio samples, and undergo non-contrast sodium MRI at 2-3 time points over 3-24 months.

Key Dates

Start date
May 12, 2025
Status verified
May 2025
Primary completion
Aug 30, 2028
Completion
Aug 30, 2028

Study Design

Enrollment
90 participants (estimated)

Arms

  • Arm: No History of AD
    Healthy controls
  • Arm: Mild AD
    Eczema Area Severity Index (EASI): scores \<7 will be considered mild AD
  • Arm: Severe AD
    Eczema Area Severity Index (EASI): scores \>21 will be considered severe

Primary Outcome Measure

Skin sodium concentration [ Time Frame: 2 years ]

Central Contacts

Locations (2)

FacilityCityStateZIPSite coordinators
San Francisco VA Medical CenterSan FranciscoCalifornia94115
Frank Asare-Bediako, BS
[email protected]
520-304-8529
Theodora Mauro, MD (PRINCIPAL_INVESTIGATOR)
UCSF Mt Zion CampusSan FranciscoCalifornia94511
Jie Zhu, MD
[email protected]
415-502-0433

Find similar trials in San Francisco, CA

By condition
Atopic dermatitis / eczema
By specialty
DermatologyRheumatologyAutoimmune disease
By research site
San Francisco VA Medical Center· San Francisco, CAUCSF Mt Zion Campus· San Francisco, CA

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