Enhanced Recovery After Surgery (ERAS) in Live Donor Kidney Transplant Recipients

Part of paid clinical trials in Fort Worth, Texas.

Sponsor
Baylor Research Institute
Study ID
NCT06997016
Phase
PHASE4
Status
Enrolling By Invitation

Conditions

  • Postoperative Pain

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • pre-operative carbohydrate drink — DIETARY_SUPPLEMENT
    50 g of carbohydrate drink 2 hours before surgery
  • Acetaminophen — DRUG
    650mg acetaminophen 30 minutes prior to surgery
  • Gabapentin — DRUG
    300 mg gabapentin 30 minutes prior to surgery
  • Bupivacaine — DRUG
    intraoperative local anesthetic
  • Ambulation — OTHER
    Assisted ambulation 12 hours after surgery

Study Details

The goal of this interventional study is to learn if an Enhanced Recovery After Surgery (ERAS) protocol works to reduce the need for narcotic pain medications in live donor kidney transplant recipients. The main questions it aims to answer are: Does the ERAS protocol lower the amount of opioid narcotic medication needed to manage post-surgery pain? Does the ERAS protocol help lower pain scores after surgery? Researchers will compare the ERAS protocol to previous patients where the ERAS protocol was not used to see if the ERAS protocol works to reduce post-surgery pain. Participants will be asked to: * Drink a pre-surgery carbohydrate drink two hours before your surgery. * Take a pre-surgery dose of Tylenol by mouth. * Take a pre-surgery dose of Gabapentin by mouth. * The surgeon will administer a local numbing medication at the surgery site by injection during the surgery. * Begin walking with assistance about 12 hours after your surgery. * Allow the research staff to collect data about your kidney function. This data will be collected on your postoperative clinic visits, which generally occur about twice weekly for one month. This information will determine your kidney health, need for hospitalization, and side effects that may occur.

Key Dates

Start date
May 5, 2025
Status verified
May 2025
Primary completion
Jun 30, 2026
Completion
Jun 30, 2027

Study Design

Enrollment
60 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Enhanced Recovery Protocol
    This group will receive the following: 50g carbohydrate drink 2 hours prior to surgery 300mg of gabapentin 30 minutes prior to surgery 650mg of acetaminophen 30 minutes prior to surgery 0.25% bupivicaine local anesthetic intraoperatively assisted ambulation 12 hours after surgery
  • No Intervention: Control group
    This group is a retrospective review of 30 patients who have undergone a live donor kidney transplant during 1/1/2022-12/31/2024 will be selected and undergo a retrospective chart review for the same data collection points.

Primary Outcome Measure

Numerical Rating Scale (NRS) (0-10) [ Time Frame: From enrollment to the end of treatment at 30 days ]

Locations (1)

FacilityCityStateZIPSite coordinators
Baylor Scott & White All Saints Medical CenterFort WorthTexas76104-

Find similar trials in Fort Worth, TX

By research site
Baylor Scott & White All Saints Medical Center· Fort Worth, TX

Related Studies