Acute Exercise and Endogenous Glucose Production in Type 2 Diabetes: Implications for Glycemic Control and Treatment of Hepatic Steatosis

Part of paid clinical trials in Orlando, Florida.

Sponsor
AdventHealth Translational Research Institute
Study ID
NCT06993454
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
25 Years - 55 Years
Healthy Volunteers
Accepted

Interventions

  • Magnetic Resonance Liver Assessment — OTHER
    Liver fat will be measured by MR imaging to assess level of hepatic steatosis.
  • Bike Exercise VO2max — OTHER
    Maximal fitness measured by cycle ergometer.
  • DEXA — OTHER
    Measure body composition (fat and lean body mass).

Study Details

The overall aim of this study is to investigate the effects of exercise on the amount of glucose that is made by the liver in people with and without Type 2 diabetes (T2D) and hepatic steatosis (fatty liver).

Key Dates

Start date
Apr 25, 2025
Status verified
Apr 2026
Primary completion
Apr 30, 2026
Completion
Apr 30, 2026

Study Design

Enrollment
12 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER

Arms

  • Other: Lean, healthy controls
    Control group.
  • Other: Individuals with T2D and hepatic steatosis
    T2D group.

Primary Outcome Measure

Measurement of Endogenous Glucose Production (EGP) [ Time Frame: Day 14 ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
AdventHealth Translational Research InstituteOrlandoFlorida32804
Recruitment Department
[email protected]
407-303-7100

Find similar trials in Orlando, FL

By condition
Type 2 diabetes
By specialty
EndocrinologyMetabolic healthWeight loss
By research site
AdventHealth Translational Research Institute· Orlando, FL

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