The Short-term Verbal Memory Endophenotype for Developmental Language Disorder Language Disorder

Part of paid clinical trials in Omaha, Nebraska.

Sponsor
Father Flanagan's Boys' Home
Study ID
NCT06968169
Status
Recruiting
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Conditions

  • Developmental Language Disorder
  • Healthy Subjects

Eligibility Criteria

Sex
ALL
Age
5 Years - 10 Years
Healthy Volunteers
Accepted

Interventions

  • Supportive learning — BEHAVIORAL
    All interventions are manipulations to the stimuli that the child hears with the goal of discovering which manipulations support verbal learning.
  • Cascades — BEHAVIORAL
    The intervention is a manipulation of word instruction with the goal of discovering whether weaker word learning results in cascading effects on semantic category memory and sentence comprehension.

Study Details

The goal of this clinical trial is to determine how memory and attention affect the ability of children with developmental language disorder (DLD) to learn and use new vocabulary.

Key Dates

Start date
Feb 9, 2025
Status verified
May 2025
Primary completion
Jun 30, 2029
Completion
Jun 30, 2030

Study Design

Enrollment
120 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: Prosody
    In Aim 1a, the syllables to be repeated are presented with English-like prosody or list-like prosody.
  • Experimental: Meaning
    In Aim 1a, the syllables to be repeated will have meaning (e.g., neck) or no meaning (e.g., ba).
  • Experimental: Grammar
    In Aim 1b, the syllables to be repeated are English adjectives and nouns. They will be presented to obey English grammar (e.g., happy pencil) or not (e.g., pencil happy).
  • Experimental: Attention
    In Aim 2, the syllables to be repeated will be presented in the 'baseline' condition or an 'attention-grabbing' condition. The attention grabbers are a reduction in the audio signal of 10dB (so that the child must listen carefully) and a visual cue (a cartoon character with large ears to cue listening carefully).
  • Experimental: Encoding
    In Aim 4, new words will be learned from instruction that involves active practice (high encoding condition) or passive study (low encoding condition).

Primary Outcome Measure

Accuracy of Syllable Repetition [ Time Frame: Day 1 ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Boys Town National Research HospitalOmahaNebraska68131-

Find similar trials in Omaha, NE

By research site
Boys Town National Research Hospital· Omaha, NE

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