A Long-Term Study of Tirzepatide (LY3298176) in Adults With Type 1 Diabetes and Obesity or Overweight

Part of paid clinical trials in Bonita, California.

Sponsor
Eli Lilly and Company
Study ID
NCT06962280
Phase
PHASE3
Status
Active Not Recruiting

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Tirzepatide — DRUG
    Administered SC
  • Placebo — DRUG
    Administered SC

Study Details

The main purpose of this study is to find out how well and how safely tirzepatide works long-term in adults who have type 1 diabetes and obesity or overweight. Participation in the study will last about 20 months.

Key Dates

Start date
May 12, 2025
Status verified
Feb 2026
Primary completion
Nov 30, 2026
Completion
Jul 31, 2027

Study Design

Enrollment
465 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Tirzepatide
    Participants will receive tirzepatide subcutaneously (SC)
  • Placebo Comparator: Placebo
    Participants will receive placebo SC

Primary Outcome Measure

Change from Baseline in Hemoglobin A1c (HbA1c) [ Time Frame: Baseline, Week 40 ]

Locations (18)

FacilityCityStateZIPSite coordinators
Kaiser Permanente Bonita Medical OfficesBonitaCalifornia91902-
AMCR InstituteEscondidoCalifornia92025-
Mary & Dick Allen Diabetes CenterNewport BeachCalifornia92663-
University Clinical Investigators, Inc.TustinCalifornia92780-
University of Colorado Anschutz Medical CampusAuroraColorado80045-
Metabolic Research Institute, Inc.West Palm BeachFlorida33401-
Iowa Diabetes and Endocrinology Research CenterWest Des MoinesIowa50266-
HealthPartners Institute dba International Diabetes CenterMinneapolisMinnesota55416-
Clinical Research ProfessionalsChesterfieldMissouri63005-
Clinvest Headlands LlcSpringfieldMissouri65807-
Las Vegas EndocrinologyHendersonNevada89074-
University of North Carolina Medical CenterChapel HillNorth Carolina27514-
Velocity Clinical Research, DallasDallasTexas75230-
Juno ResearchHoustonTexas77040-
Southern Endocrinology AssociatesMesquiteTexas75149-
Texas Diabetes & Endocrinology, P.A.Round RockTexas78681-
San Antonio Clinical TrialsSan AntonioTexas78240-
Texas Valley Clinical ResearchWeslacoTexas78596-

Find similar trials in Bonita, CA

By condition
Obesity / overweightType 1 diabetes
By specialty
EndocrinologyMetabolic healthWeight loss
By research site
Kaiser Permanente Bonita Medical Offices· Bonita, CAAMCR Institute· Escondido, CAMary & Dick Allen Diabetes Center· Newport Beach, CAUniversity Clinical Investigators, Inc.· Tustin, CAUniversity of Colorado Anschutz Medical Campus· Aurora, COMetabolic Research Institute, Inc.· West Palm Beach, FL

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