Changes in Glucose Tolerance in Patients With Cirrhosis Peri-Liver Transplant

Part of paid clinical trials in Chicago, Illinois.

Sponsor
University of Chicago
Study ID
NCT06950788
Status
Recruiting
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Conditions

  • Cirrhosis, Liver
  • Diabetes Mellitus Risk
  • Transplant-Related Disorder
  • Transplant; Failure, Liver

Eligibility Criteria

Sex
ALL
Age
18 Years - 75 Years
Healthy Volunteers
Not accepted

Study Details

The goal of this observational study is to establish risk factors for post-transplant in adult individuals with cirrhosis without diabetes undergoing liver transplant evaluation. The question being addressed is: can laboratory work, anthropometric tests, functional tests, imaging, and advanced measurements such as wrist actigraphy, continuous glucose monitoring, or oral glucose tolerance testing predict the development of diabetes after liver transplant? Participants will be asked to periodically participate in wearing a continuous glucose monitor and wrist actigraph and obtain an oral glucose tolerance test both before and after liver transplant.

Key Dates

Start date
Mar 12, 2024
Status verified
May 2026
Primary completion
Jun 30, 2027
Completion
Jan 31, 2031

Study Design

Enrollment
60 participants (estimated)

Primary Outcome Measure

Early post-transplant hyperglycemia [ Time Frame: 45 days after transplant ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Chicago Medical CenterChicagoIllinois60637
Alan L Hutchison, MD, PhD
[email protected]
773-702-1000
Mary E Rinella, MD
[email protected]
Mary E Rinella, MD (SUB_INVESTIGATOR)
Celeste C Thomas, MD (SUB_INVESTIGATOR)
Alan L Hutchison, MD PhD (PRINCIPAL_INVESTIGATOR)

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By research site
University of Chicago Medical Center· Chicago, IL

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