Neurophysiological Benefits of Live Music for Early Alzheimer's Patients and Their Caregivers

Part of paid clinical trials in New Haven, Connecticut.

Sponsor
Yale University
Study ID
NCT06940687
Status
Enrolling By Invitation

Conditions

Eligibility Criteria

Sex
ALL
Age
50 Years - 80 Years
Healthy Volunteers
Not accepted

Interventions

  • Pre-recorded Music Session — BEHAVIORAL
    A pre-recorded concert session
  • Live Music Session — BEHAVIORAL
    A 45-minute live music performance

Study Details

This study aims to investigate the neurophysiological effects of live music on individuals with early Alzheimer's Disease (AD), dementia, and/or mild cognitive impairment (MCI) and their caregivers. Heart rate (HR), heart rate variability (HRV), and brain activity will be measured as participant-caregiver dyads listen to preferred and improvised music performed by professional musicians. Investigators will leverage various measurement techniques including, but not limited to, electroencephalography (EEG), behavioral, surveys, and physiological monitoring to study the impact of live music on anxiety in AD and inter-dyad synchrony.

Key Dates

Start date
Jan 28, 2025
Status verified
Feb 2026
Primary completion
Mar 22, 2026
Completion
Mar 22, 2026

Study Design

Enrollment
60 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE

Arms

  • Experimental: AD / Dementia / MCI participants and caregivers dyads with music
    Each participant will take part in two sessions. Both sessions will last up to 3 hours. Participants will attend a series of live music performances and pre-recorded control session performances. Physiological and survey data will be collected to assess the impact of live versus pre-recorded music on anxiety, social motivation, parasympathetic activity, and neural synchrony.

Primary Outcome Measure

Change in EEG activity during live music vs pre-recorded music conditions [ Time Frame: Day 1 and Day 2, an average of 1 week apart ]

Locations (2)

FacilityCityStateZIPSite coordinators
Firehouse 12 StudiosNew HavenConnecticut06510-
Musical Intervention StudiosNew HavenConnecticut06520-

Find similar trials in New Haven, CT

By condition
Alzheimer's disease
By specialty
NeurologyDementia careBrain disordersGeriatrics
By research site
Firehouse 12 Studios· New Haven, CTMusical Intervention Studios· New Haven, CT

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