Effect of a Cepham Supplement on Hot Flashes and Menopausal Symptoms in Postmenopausal Women

Part of paid clinical trials in Jacksonville, Florida.

Sponsor
Jacksonville University
Study ID
NCT06939868
Status
Not Yet Recruiting

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Conditions

  • D008593

Eligibility Criteria

Sex
FEMALE
Age
40 Years - 60 Years
Healthy Volunteers
Accepted

Interventions

  • Shatavari Root Extract, oral capsule — DIETARY_SUPPLEMENT
    This intervention consists of a proprietary, standardized extract of Asparagus racemosus (Shatavari), formulated specifically for women's health and cognitive support. The supplement is provided in oral capsule form and standardized to a specific concentration of shatavarin IV, the primary active compound. Participants will take one capsule daily for 30 days. This formulation, known as SheVari4™, is patent-pending and manufactured by Cepham, designed to address vasomotor symptoms (hot flashes) and other menopausal concerns. It is distinct from other Shatavari supplements in its standardization and use in a placebo-controlled, double-blind trial targeting postmenopausal women.

Study Details

The goal of this clinical trial is to learn if a daily nutritional supplement can reduce hot flashes and other menopausal symptoms in postmenopausal women. The main questions this study aims to answer are: Does the supplement reduce the number and severity of daily hot flashes? Does it improve other common menopausal symptoms? Researchers will compare the supplement to a placebo (a look-alike capsule with no active ingredients) to see if it helps manage symptoms during menopause. Participants will: Take either the supplement or a placebo daily for 30 days Track their hot flashes each day using a short online survey Complete a symptom questionnaire at the beginning and end of the study This study is for women ages 40-60 who have been postmenopausal for at least one year and currently experience bothersome hot flashes.

Key Dates

Start date
May 1, 2025
Status verified
Apr 2025
Primary completion
Aug 30, 2025
Completion
Sep 30, 2025

Study Design

Enrollment
44 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Active Comparator: Supplement Group
  • Placebo Comparator: Placebo Group: Sugar pill

Primary Outcome Measure

Composite hot flash score: Frequency × Severity [ Time Frame: 30 days ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Jacksonville UniversityJacksonvilleFlorida32211
Heather A Hausenblas, PhD
904-891-9746
Stephanie L Hooper, MPH
908-868-8740

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