Effect of Flavored, Carbonated Drinks on Salivary Flow, Salivary Composition, and Taste Perceptions

Part of paid clinical trials in Valhalla, New York.

Sponsor
PepsiCo Global R&D
Study ID
NCT06933290
Status
Recruiting
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Conditions

  • Saliva Production
  • Taste Perception

Eligibility Criteria

Sex
ALL
Age
18 Years - 45 Years
Healthy Volunteers
Accepted

Interventions

  • Beverage — OTHER
    15 milliliter aliquot interspersed with tastants with a 3 minute break between tastants

Study Details

To determine the effect of flavored, carbonated drinks on salivary flow rate, saliva composition, and taste perceptions compared with control drinks (water, carbonated water, non-carbonated)

Key Dates

Start date
Mar 24, 2025
Status verified
Apr 2025
Primary completion
Jun 13, 2025
Completion
Jun 29, 2025

Study Design

Enrollment
13 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: Flavored carbonated drink 1
    Flavored carbonated beverage with nutritive sweeteners
  • Experimental: Flavored carbonated drink 2
    Flavored carbonated beverage with non-nutritive sweeteners
  • Experimental: Flavored drink
    Flavored non-carbonated beverage with nutritive sweeteners
  • Experimental: Flavored non-carbonated drink
    Flavored non-carbonated beverage with non-nutritive sweeteners
  • Experimental: Carbonated Water
    Unflavored carbonated water
  • Experimental: Water
    Plain, unflavored, non-carbonated water

Primary Outcome Measure

Salivary flow rate [ Time Frame: At each of six 2 hour test sessions 2-8 days apart at same time of day ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Gatorade Sports Science InstituteValhallaNew York10595
Lindsay Baker, PhD
[email protected]
814-883-9454
Michelle King, PhD
[email protected]
815-441-2988

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By research site
Gatorade Sports Science Institute· Valhalla, NY

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